Our big dinoflagellate paper is out! Highlights include transcriptomes for 39 heterotrophic species and new insights into character evolution of notable traits, like chromatin packaging proteins and rhodopsins. Enjoy! doi.org/10.1016/j.ympe…

The peer-reviewed version of our study on the evolution of tissue-specific expression across vertebrates and insects is finally published in NatureEcoEvo ! Federica Mantica Centre for Genomic Regulation (CRG) UPF Medicine and Life Sciences

nature.com/articles/s4155…

Extended deadline 🗓️April 30

The choice of whether to use Seurat or Scanpy for single-cell RNA-seq analysis typically comes down to a preference of R vs. Python. But do they produce the same results? In biorxiv.org/content/10.110… w/ Joseph Rich et al. we take a close look. The results are 👀 1/🧵

🔥 story lead by Michael Scherer & Indranil Singh, with Alejo Rodriguez-Fraticelli, PhD: epimutations stably mark clones in hematopoiesis over months and years, and can be read out at scale using targeted single-cell, single-CpG-resolution profiling of DNA methylation🧵biorxiv.org/content/10.110…

We have a 2y postdoc position open in my group. The profile is quite broad, from bioinformatics to molecular biology. If you are interested in giant virus endogenization, EvoDevo, epigenetics and evolution, do apply and gent in touch. Please RT. Details: qmul.ac.uk/jobs/vacancies…

📣 Excited to introduce our #OrganizingCommittee , leading its team to success at the upcoming Congress in #Barcelona .

🌟 Don't miss the chance to join #ESEB2025 and get an extra 5% off with Pre-Registration.

Secure your place ➡️ eseb2025.com/pre-registrati…

Toni Gabaldón

Please see new paper describing single cell atlas of Xenoturbella. A huge effort from
Helen and a great collaboration with Heather Marlow and
Arnau Sebé Pedrós. Thanks so much to all co-authors.
(Download here: rdcu.be/dBMxf)

nature.com/articles/s4146…

🚨Job alert 🚨 We have an open 3-year research technician post to work with Allan Carrillo-Baltodano Margarida Cardoso Moreira and Dave Ferrier in the evolution of DV specification and developmental system drift in 🪱 and spiral cleavage.

Close: 2 April

Apply! qmul.ac.uk/jobs/vacancies…

+ info DM

Join the IBIS Challenge: an open competition focused on the computational prediction of transcription factor binding motifs. IBIS aims to advance state-of-the-art methods for Inferring Binding Specificities of human transcription factors from diverse experimental data. (1/12)

Does regeneration re-use developmental regulatory networks?
PhD position in experimental and computational biology, in our team with Mathilde Paris +Arnau Sebé Pedrós.
Use single-cell omics to reconstruct and compare GRNs underpinning leg development and regeneration.
averof-lab.org/pages/replay

The peer-reviewed version of our study on how an eutherian-specific isoform of SUZ12 decouples local from global PRC2 activity is out in Molecular Cell!

Great work by Niccolò Arecco & Ivano Mocavini, a perfect collaboration with the polycomb masters
Di Croce Lab!

👉authors.elsevier.com/c/1iiyW3vVUPRl…

Please share our obituary of the wonderful Claus Nielsen. A huge contributor to the study of animal evolution + a very nice man. Happy to have known him for almost 30 yrs since I first wrote to him (a letter!) during my PhD. With Andreas Hejnol +
Arendt Lab.
nature.com/articles/d4158…

Nucleosomes at the dawn of eukaryotes. Antoine Hocher and I discuss the earliest steps in the evolution of the nucleosome from the vantage point of archaea. Asgardarchaeal histones, the evolution of tails, heterodimerization, and much much more. academic.oup.com/gbe/advance-ar…

Proudly presenting our new findings on how #RNA binding proteins (RBPs) may increase the tolerance of genomes to transposable element (TE) insertions. If you want to know more read this thread or our story nature
nature.com/articles/s4158…

Join us for this conference in Madrid: chromatin, single-cell, functional genomics, CRISPR and more.
Great speaker line-up and beautiful venue. Also...best time of the year to visit Madrid!
Fundación ”la Caixa”
Centre for Genomic Regulation (CRG)
Cambridge University haem.cam.ac.uk/events/genome-…
#Genomics #Cancer