Total Synthesis and Methodology Highlights
@totalsyntheses
Highlight Total Synthesis, Organometallic Chemistry, Heterocycles Synthesis, Biosynthesis, Medicinal Chemistry, Electrochemistry and Photochemistry.
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23-12-2016 17:44:51
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Been waiting for this one to come out - photochem conversion of broad HetAr-CO2H monomer set to halides - really neat work out in J. Am. Chem. Soc. Asap from The Castellano Group NC State Chemistry MacMillan Group and #PfizerChemistry Anne Marie schmitt #ChemCollabs doi.org/10.1021/jacs.2…
A Unified Approach to Decarboxylative Halogenation of (Hetero)aryl Carboxylic Acids David MacMillan MacMillan Group Princeton Chemistry Total Synthesis and Methodology Highlights Pfizer Inc. NC State University NC State Chemistry The Castellano Group Phil Castellano #decarboxylative #Halogenation #Hetaranes pubs.acs.org/doi/10.1021/ja…
Synthesis of Dimeric Securinega Alkaloid Flueggeacosine B: From Pd-Catalyzed Cross-Coupling to Cu-Catalyzed Cross-Dehydrogenative Coupling @KAIST #TotalSynthesis Total Synthesis Total Synthesis and Methodology Highlights #Alkaloid #Pd #CrossCoupling #Cu #Dehydrogenative pubs.acs.org/doi/10.1021/ja…
Two-Stage Syntheses of Clionastatins A and B @CHNSci Total Synthesis Total Synthesis and Methodology Highlights #Synthesis #Clionastatins #Chlorination pubs.acs.org/doi/10.1021/ja…
Versatile Palladium-Catalyzed Approach to Acyl Fluorides and Carbonylations by Combining Visible Light- and Ligand-Driven Operations McGill University Total Synthesis and Methodology Highlights #Palladium #Fluorides #Light pubs.acs.org/doi/10.1021/ja…
Ever wondered about directly turning the indole skeleton of a bioactive compound into a quinazoline or quinoxaline by "just" inserting a N atom? Check this MS ChemRxiv from Julia, Ori Green, Allegra Franchino, Patrick Finkelstein. doi.org/10.26434/chemr…
Happy to report a practical bottom-up synthesis of aminoglycoside antibiotic ribostamycin!!! Collaborative efforts with Peng Liu Group. Novel asymmetric catalytic desymmetrization of ⌬ (♡!), mechanism, com. studies, and more! nature.com/articles/s4416…
Introducing the Catalytic Amination of Silanes via Nitrene Insertion Pedro J. Perez CIQSO Univ. of Huelva Maseras Group ICIQ BIST-Barcelona Institute of Science and Technology #Catalytic #Amination #Silanes #Nitrene Total Synthesis and Methodology Highlights pubs.acs.org/doi/10.1021/ja…
Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silyl Ethers AK List Ben List Hokkaido University ICReDD #Organocatalysis Total Synthesis and Methodology Highlights #Silyl #Stereogenic #Silylethers pubs.acs.org/doi/10.1021/ja…
Synthesis of Pleuromutilin UCI Chemistry UC Irvine Total Synthesis Total Synthesis and Methodology Highlights #Pleuromutilin #Total #Synthesis pubs.acs.org/doi/10.1021/ja…
JACS online: Asymmetric Total #Syntheses of #Cephalotane-Type #Diterpenoids #Cephanolides A–D J. Am. Chem. Soc. Top Science @CHNSci Peking University Tianjin University Total Synthesis Total Synthesis and Methodology Highlights #Chemistry #Science #Catalysis #technology pubs.acs.org/doi/10.1021/ja…
JACS online: #Symmetry-Driven Total #Synthesis of #Myrioneurinol J. Am. Chem. Soc. Top Science @CHNSci @UTSWNews Total Synthesis Total Synthesis and Methodology Highlights #Chemistry #Science #Catalysis #technology pubs.acs.org/doi/10.1021/ja…
Check out our recent syntheses of bufospirostenin A and ophiopogonol A in only seven steps from inexpensive starting materials just out in J. Am. Chem. Soc. . Great collaboration with Hong group from Zhejiang University for computational studies: pubs.acs.org/doi/10.1021/ja…
Excited-State Copper-Catalyzed [4 + 1] Annulation Reaction Enables Modular Synthesis of α,β-Unsaturated-γ-Lactams SUNY - The State University of New York Total Synthesis and Methodology Highlights #Cu #ExcitedState #Annulation #Modular #Lactams #Enamides pubs.acs.org/doi/10.1021/ja…
Concise Synthesis of (−)-GA18 Methyl Ester Mingji Dai Purdue University Emory Chemistry Emory University Total Synthesis and Methodology Highlights Total Synthesis #Synthesis #2plus2 #Transhydrindane #Gibberellins pubs.acs.org/doi/10.1021/ja…