Penn Heme Onc Fellows grad dinner. Quaker meeting style to honor and thank this amazing class.Residents at the start of COVID & fellowship so disrupted by COVID. @dhjutsw1 Penn Medicine Duke Cancer Univ of MINN Penn Medicine - Abramson Cancer Center lucky to recruit from this class. Tim Brown, MD MSCE

Ruchi Patel from the Ruella Lab at Penn Medicine shows that CD5 deletion enhances CART function in multiple liquid and solid cancer models by enhancing T cell effector functions. Soon first-in-human trial for T-cell lymphoma with viTToria biotherapeutics #ASH23

Yunlin Zhang is ready to present her poster on a first-in-human CART19 targeting a non-FMC63 CD19 epitope with low avidity. Ruella Lab #ASH23 published today! Ruchi Patel molecular-cancer.biomedcentral.com/articles/10.11…

Puneeth Guruprasad from the Ruella Lab showing our newest data on the role of modulation of BTLA in CART immunotherapy #ASH23 Penn Medicine

Tazemetostat enhances #CART immunotherapy for #NHL. Patrizia Porazzi from our Ruella Lab presenting her newest results at #ASH23 Penn Medicine ASH Clinical News Saad kenderian

#NHL #HCL cell targeting with #CART but no B-cell aplasia? It might be possible with VH4-34 CART as presented at #ASH23 by Ivan Cohen of the Ruella Lab from Penn Medicine Saad kenderian

Working hard to make CAR T cell safer and understanding the pathogenesis of CRS. #ASH2023 Marco Ruella Ruella Lab Society for Immunotherapy of Cancer

Strong work Dr. Puneeth Guruprasad you killed it. First grad student out of Ruella Lab.

OCE welcomes Christopher Tor Sauter C. Tor Sauter to the DHM2 lymphoma team! He obtained his medical degree Emory School of Medicine and did internal medicine residency and Hematology/Oncology Fellowship Penn Medicine. He enjoys hiking, camping & canoeing with his wife and kids. #OCECareers

FDA approves durvalumab with chemotherapy for mismatch repair deficient primary advanced or recurrent endometrial cancer. fda.gov/drugs/resource… #OCENewsBurst

Grateful to #ASH2024 for the chance to present our work on overcoming the absence of CD2:CD58 co-stimulation using an innovative PD1:iCD2 switch receptor. Thanks to my mentor Marco Ruella and the Ruella Lab for their invaluable support. Excited to delve deeper into this approach!

Wild experience to have seen our story shared at the #ASH24 Plenary in San Diego by my wonderful co-lead Shan Liu ! Looking forward to further proving that we can enhance cancer treatment by modulating readily-actionable patient lifestyle factors.

New research finds that a ketogenic diet enhances CAR T Cell antitumor function via β-Hydroxybutyrate ft. Shan Liu, @MaayanLevy_Lab (Penn Microbiology), Puneeth Guruprasad (Penn Medicine), Marco Ruella & Elise Chong (Penn Medicine - Abramson Cancer Center) tinyurl.com/4tw6eddy

Exciting news: EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models Cancer Cell Marco Ruella Alberto Carturan Puneeth Guruprasad Ruchi Patel Yunlin Zhang Guido Ghilardi and my stellar co-author Siena Nason cell.com/cancer-cell/ab…