oh, nice, Spotify just killed the best feature of their API - Audio Analysis - and more. developer.spotify.com/blog/2024-11-2…

𝐍𝐞𝐰 𝐇𝐞𝐢𝐠𝐡𝐭𝐬 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐀𝐠𝐬. 🗻 🗞️: bit.ly/3VVFbc3 #GoAgs | #JoiningTheAscent

I don’t think anyone who publicly equates a high polygenic risk score with actually having the associated phenotype should be allowed to run a genetic testing company. Egregious abuse of consumers’ trust in you to communicate information about their health.

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis

professor watching her advisees on the job market

Unfounded claims about basic concepts in statistics and population genetics will destroy trust with consumers who lack the background to investigate facts themselves. These products are based on statistical tests called GWAS that provide measures of "heritability": precise

People are mad about PRS but the actual problem here is running carrier screening at 30x doesn’t let you do the paralog calling required to cover all the common single gene disorders (sma, alpha-thalassemia, etc).

"Finding the Best Sleep Tracker" Results of an experiment where I wore 4 sleep trackers every night for 2 months. TLDR Whoop >= Oura > 8Sleep >> Apple Watch + AutoSleep. Link simply right here instead of in a reply because ¯\(ツ)/¯ karpathy.bearblog.dev/finding-the-be…

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by U.S. FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,

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There are few in this world who were such forces for good as Atul Butte. His dazzling intellect, relentless curiosity, generosity of spirit, boundless charisma, and infinite optimism left a mark on everything he touched and everyone lucky enough to know him. An enormous loss.

My lab was totally destroyed tonight by an Iranian missile. Nobody was hurt. Flies, plasmids, cells, equipment - all gone. Heart breaking. If during the course of the past 16 years, you have received something from my lab - please keep them safe.

מכון ויצמן התקבל בוואצאפ, אתן קרדיט אם יהיה

Oof. Polygenic scores for IQ lose 75% of their explained variance when adding family controls, even worse than the attenuation for Educational Attainment. These are the scores Silicon Valley is using to select embryos 😬. A few thoughts on this study ...

Today, we report Germinal, a method for efficient de novo antibody design, with Santiago Mille and Xiaojing Gao. Germinal achieves success rates of 4-22% across diverse epitopes. We make the work fully open, without doing lame things like posting a preprint without methods. 🧵

Appreciate the spotlight from SportsCenter 🐴 ICYMI, our Bold Aqua uniforms debuting tonight were featured this morning on ESPN’s Gear Up segment. #GoAgs | #Shredville

Calling on all scientists to call out hype, grift & BS when u see it. If u don't, u risk anti-science grifters leveraging overhyped & underdelivered promises & shoddy science to destroy public trust in the enterprise. Keep science & science comm grounded & truthful.

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It was extremely obvious from the start that Nucleus had no idea what they were doing and was selling snake oil. More people should have spoken up before Nucleus inked deals with IVF clinics and rolled out a massive NYC ad campaign.

one of the core tensions in this industry is the fact that most companies recognize they're working on an incredibly sensitive topic they know the general population will need to be slowly and tactfully acclimated to the idea of advanced family planning Nucleus is perceived as