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I don't think we have great evidence. I think potable water is fine - doesn't have to be distilled or sterile. But I don't know evidence about volume infused directly into jejunum / small intestine.

This is where medicine is headed - integration of Bioinformatics tools within the EHR (and studying their effect on patient outcomes). Exciting work.

Great pair of studies and lots to talk about. Amazing how HFNC has changed many of our practices in the ICU.

Lots of fun answering the great questions from the listeners. And some nitty gritty discussion of oxygen targets in trauma patients and transfusion targets in patients with subarachnoid hemorrhage. We've discussed these topics before, but not in these populations.

Yes. This study still scares me. It essentially supports the hypothesis that ICH might be infectious or contagious. When you consent for blood transfusions, when have you ever said, "Oh, and you might get an intracranial hemorrhage later in your life"?

Peter Edmonds ICUEdandToddCast Todd Rice well that is absolutely aweful

Yes, I completely agree - medicine is a vast ocean of information that we don't know or don't understand. It is why it is a profession of continual learning - always learning knew information.

Important ?? in the care of pts on VV-ECMO. We worry about clotting the circuit/oxygenator, but multiple studies have now shown pts have more morbidity/mortality from bleeding than clotting. Maybe with newer technology, etc, the need for systemic anticoagulation isn't needed?

We don't think about "circadian rhythm" of our feeding. But it is part of the day/night cycle. Is part of the reason our ICU patients get delirium or day/night confusion because we take away the circadian rhythm of diet? Fascinating to think about.

Yep. The ? is what can we do to overcome this anabolic resistance (and hint hint, the answ't provide higher levels of protein alone). Is it reduce inflammation? Stimulate the muscle? Anabolic steroids? something else? I predict this will be a big part of future of ICU nutrition.

HFNC has truly changed the way that we practice. And we still have lots to learn about it (like when to optimally use it and how best to wean it). Great discussion around where things currently stand with regards to HFNC and what we still need to figure out.

Awesome conference. State of the art training - both didactic and hands-on/simulation. A can't miss event. And that doesn't even consider that it is in Nashville - so nightlife is also tons o' fun.

Inhaled sevoflurane - used more during the pandemic with shortages of other sedatives - but now we have an RCT evaluating its effects. Excellent study and great discussion.

There are case series / cohorts for its use in post-op vasoplegia (which is obviously a known complication of cardiopulm bypass). The use of Angiotensin 2 in the post-op vasoplegia realm is definitely increasing. I don't know of any RCTs of it for this indication.

Great topic. PE's are (unfortunately) a condition which we commonly see in the ICU. Data on best treatments is evolving and lots to learn.

Reiterating how great this boot camp is. Great learning. Hands on learning opportunities. Outstanding didactics. And you can leave to go party in Nashville before my "Fever 2" talk. 😂

Really tried to dissect this study. Results are contrary to previous study findings. Just when I thought I had an idea about using steroids in CAP, this prompted a re-visit. Well worth a listen to hear the discussion and us floundering at the end as to how this affects practice.

More data suggesting there might not be a single best sedative for all critically ill (mech vent) pts. Ongoing study should look at phenotypes and use of different sedatives and whether the sedative agent should be dynamic across a patient's critical care course. Edward Qian

Lots of good stuff to talk about - and what scores will the A2B "acronym" receive

Although somewhat infrequent in our ICU admissions, acute chest syndrome is often complex with high morbidity. New treatments are badly needed. Appreciate Dr. Tillman joining us to discuss this RCT and the possibility of systemic anticoagulation benefitting these unfortunate pts.