ほーくあい MD/PhD@Breast Oncology
@tkdmhawkeye
デトロイト近郊→日本。乳がん専門医・腫瘍内科医。成人。空手弐段/書道八段/ちょこっとバレエ・乗馬。MD/PhD, MedOnc @ Breast Oncology
ID: 160937620
29-06-2010 14:32:57
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What mediates resistance to T-DXd? Large study (n=2799) by George W Sledge MD et al. suggests the relevance of baseline ABCC1 levels (efflux pump) and finds emerging mutations in NFE2L2 (activator of ABCC1) and KEAP1 (negative regulator of NFE2L2) post T-DXd. nature.com/articles/s4152…