Pasare Lab
@thepasarelab
Welcome to the Pasare Lab at CCHMC. Our lab studies TLR signaling pathway and how activation of TLRs influence the shaping of the adaptive immune responses.
ID: 1020367638646743040
20-07-2018 17:59:37
39 Tweet
474 Followers
43 Following
Congrats Pasare Lab Leah Kottyan on manuscript showing TLR4 signaling in Mf, but not monocytes, enables nuclear translocation of IRF1, which acts as a pioneer TF to increase the chromatin accessibility of IFNB1 and ISG loci. cell.com/cell-reports/p…
Not all phagocytes respond similarly to TLR ligands--an important examination of the role of IRF1. Kudos to Pasare Lab and colleagues on this important discovery. cell.com/cell-reports/f…
Allergens activate Ripoptosome to drive Caspase-8 mediated cleavage of IL-33.A step closer to type II sensor? Rothenberg CURED Research Lab Pasare Lab Cincinnati Children's nature.com/articles/s4159…
Study Nature Immunology reveals how the body's innate #ImmuneSystem senses allergens like #mites, #insects and #fungi. Suggests new targets for treatment. Congrats Rothenberg CURED Research Lab Pasare Lab ! #inflammation #allergies #foodallergies scienceblog.cincinnatichildrens.org/discovery-of-r…
CD4 T effector memory T cells engage TNFR and CD40 on DCs to cause auto-immune pathology and cytokine storm. New targets for combating T cell induced innate inflammaton. Pasare Lab @_m_mcdaniel Aakanksha Jain Cincinnati Children's CCHMC Immunology Grad Program science.org/doi/10.1126/sc…
Potential Approach Emerges to Treat Autoimmunity and Prevent Serious Side Effects of #Cancer Immune Therapies. Congrats to Pasare Lab CincyChildren's CBDI #cytokinestorms scienceblog.cincinnatichildrens.org/potential-appr…
Division of Immunobiology Cincinnati Children's is looking for a new leader. Great place to do exceptional science. Please spread the word and apply jobs.cincinnatichildrens.org/search/jobdeta…
IEC-intrinsic IL-1R enhances IL-22–induced AMPs for protection vs C. rodentium, but contributes to damage-induced inflammation via chemokines & ROS. Congrats Hannah, Garrett, Lisa & Pasare Lab Kelli VanDussen Theresa Alenghat CCHMC Immunology Grad Program doi.org/10.1084/jem.20…
Overcast, Meibers et al. Pasare Lab Cincinnati Children's characterize the dual role of IL-1R signaling in IECs during C. rodentium infection and DSS-induced #colitis. bit.ly/3KaPqn7 #MucosalImmunology #InnateImmunity #inflammation
Effector memory CD4 T cells drive DNA damage in Dendritic cells to activate non-canonical STING pathway and subsequent innate inflammation. Stellar work by Hannah Meibers, a graduate student in the lab Cincinnati Children's CCHMC Immunology Grad Program Pasare Lab cell.com/cell-reports/f…
CCHMC Division of Immunobiology is hiring faculty (at all ranks). Applicants should send a CV, 2-page research plan, and contact information for three references to [email protected] by March 1st, 2024.
Activation of the innate immune system by memory T cells (not PAMPs) is the primary driver of transplant rejection Pasare Lab Cincinnati Children's pnas.org/doi/10.1073/pn…
Join us Cincinnati Children's to do exciting research in Immunology. Please apply and forward to colleagues. nature.com/naturecareers/…
Congratulations! Nandan. Delighted that Nandan Gokhale will be on the faculty of the Division of Immunobiology Cincinnati Children's soon. Can't wait to see how his exciting research unfolds. Welcome! Nandan.
I had once said to Rana " It is not possible to reverse fibrosis" She is well on her way to prove me wrong. Huge implications for diseases where fibrosis results in morbidity and mortality. Congratulations! Rana Herro rana herro Cincinnati Children's
