Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS

@thebeaniac

Staff Internist and Nephrologist at YRH, Alumnus UofT & MPUH, Master's @Mcmaster's U #NSMC 2021๐ŸŽ“, @onconephsociety #ASDIN @ISNKidneycare SoMe member

ID: 1076690553016909825

calendar_today23-12-2018 04:06:46

1,1K Tweet

1,1K Followers

832 Following

Rowan Zyada (@rowanzyada) 's Twitter Profile Photo

1/n ๐ŸšจWelcome to #NephMadness tweetorial on Gila Monster ๐ŸฆŽ How can Gila The NephMadness Monster, who lives in the deserts help with the obesity epidemic? According to World Health Organization (WHO), globally 1/8 persons is obese ๐Ÿ‘‡ who.int/news-room/factโ€ฆ

1/n
๐ŸšจWelcome to #NephMadness tweetorial on Gila Monster ๐ŸฆŽ
How can <a href="/Gila_NephMad/">Gila The NephMadness Monster</a>, who lives in the deserts help with the obesity epidemic?
According to <a href="/WHO/">World Health Organization (WHO)</a>, globally 1/8 persons is obese ๐Ÿ‘‡
who.int/news-room/factโ€ฆ
ISN Education (@isneducation) 's Twitter Profile Photo

We are delighted to start a new term with our amazing members of the Social Media Team ๐Ÿ™Œ Welcome to our new members Milagros Flores๐Ÿ‡ฒ๐Ÿ‡ฝ๐Ÿ‡ญ๐Ÿ‡ณ Srikanth Bathini๐Ÿ‡ฎ๐Ÿ‡ณ and Hamza Rage๐Ÿ‡ธ๐Ÿ‡ด Looking forward to working together ๐Ÿคœ๐Ÿค›

We are delighted to start a new term with our amazing members of the Social Media Team ๐Ÿ™Œ

Welcome to our new members <a href="/dra_miliflores/">Milagros Flores</a>๐Ÿ‡ฒ๐Ÿ‡ฝ๐Ÿ‡ญ๐Ÿ‡ณ <a href="/dakidneydoc/">Srikanth Bathini</a>๐Ÿ‡ฎ๐Ÿ‡ณ and <a href="/hmzrage/">Hamza Rage</a>๐Ÿ‡ธ๐Ÿ‡ด Looking forward to working together ๐Ÿคœ๐Ÿค›
Int Society of Nephrology (@isnkidneycare) 's Twitter Profile Photo

๐Ÿ“ข #Tweetorial alert! โ€œNo decision about me, without me!โ€ Yes, this is the new mantra for patients with kidney failure before making a valid choice of treatment modality. Letโ€™s talk about Shared Decision Making (SDM) in Dialysis in this #ISNTweetorial ๐Ÿงต

Int Society of Nephrology (@isnkidneycare) 's Twitter Profile Photo

๐—ฆ๐—”๐—ฉ๐—˜ ๐—ง๐—›๐—˜ ๐——๐—”๐—ง๐—˜ for the next ISN North America and the Caribbean Regional Board-Caribbean College of Family Physicians webinar: "Approach to the Patient with an Elevated Serum Creatinine" ๐Ÿ—ฃ๏ธ Edgar V. Lerma ๐Ÿ‡ต๐Ÿ‡ญ ๐Ÿ—“๏ธ June 27 ๐Ÿ•– 7 pm GMT-5 ๐Ÿ”— Free registration: us02web.zoom.us/meeting/registโ€ฆ

๐—ฆ๐—”๐—ฉ๐—˜ ๐—ง๐—›๐—˜ ๐——๐—”๐—ง๐—˜ for the next ISN North America and the Caribbean Regional Board-<a href="/caricoll_family/">Caribbean College of Family Physicians</a> webinar: "Approach to the Patient with an Elevated Serum Creatinine"

๐Ÿ—ฃ๏ธ <a href="/edgarvlermamd/">Edgar V. Lerma ๐Ÿ‡ต๐Ÿ‡ญ</a> 
๐Ÿ—“๏ธ June 27
๐Ÿ•– 7 pm GMT-5
๐Ÿ”— Free registration: us02web.zoom.us/meeting/registโ€ฆ
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

๐Ÿ“MGRS - evaluation and management by Dr. Nelson Leung โœ”๏ธHow to detect, the importance of using different techniques, Rx algorithm, post kidney tx MGRS recurrence management #MSKOncoNephCME American Society of Onconephrology

๐Ÿ“MGRS - evaluation and management by Dr. Nelson Leung
โœ”๏ธHow to detect, the importance of using different techniques, Rx algorithm, post kidney tx MGRS recurrence management

 #MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

๐Ÿ“AL amyloidosis - 50-60% renal involvement, Dara based Rx - Kidneys take time to recover. โžก๏ธ Newer immunotherapeutic approaches, bispecific abs, amyloid directed Rx in development. #MSKOncoNephCME American Society of Onconephrology

๐Ÿ“AL amyloidosis - 50-60% renal involvement, Dara based Rx - Kidneys take time to recover.

โžก๏ธ Newer immunotherapeutic approaches, bispecific abs, amyloid directed Rx in development.

#MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

Amyloidosis: - prognostic factors for renal survival, amyloid renal response criteria based on proteinuria and IMWG renal response criteria based on eGFR criteria. - Notably there are still some lacunae in IMWG criteria which needs a relook. #MSKOncoNephCME American Society of Onconephrology

Amyloidosis:

- prognostic factors for renal survival, amyloid renal response criteria based on proteinuria and IMWG renal response criteria based on eGFR criteria.

- Notably there are still some lacunae in IMWG criteria which needs a relook.

#MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

Pathology - Dr. Samih Nasr: โžก๏ธ Unmasking with paraffin stain is important for ruling out monotypic fibrillary GN, MN and IgAN which are mostly polyclonal โžก๏ธ importance of IgG subtyping in MGRS โžก๏ธ uses of ancillary techniques in Onco-Neph Dx #MSKOncoNephCME American Society of Onconephrology

Pathology - Dr. Samih Nasr: 

โžก๏ธ Unmasking with paraffin stain is important for ruling out monotypic fibrillary GN, MN and IgAN which are mostly polyclonal
โžก๏ธ importance of IgG subtyping in MGRS
โžก๏ธ uses of ancillary techniques in Onco-Neph Dx

#MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

๐Ÿ“CART cell Rx: ๐Ÿ—๏ธ Product comparison for indications, CRS rate and median onset of CRS. ๐Ÿ—๏ธ Management of severe CRS refractory to Tocilizumab + steroids ๐Ÿ—๏ธ CD 19 CART rx in SOTs ๐Ÿ—๏ธ Application spectrum of CART rx in SOTRs #MSKOncoNephCME American Society of Onconephrology

๐Ÿ“CART cell Rx:

๐Ÿ—๏ธ Product comparison for indications, CRS rate and median onset of CRS.

๐Ÿ—๏ธ Management of severe CRS refractory to Tocilizumab + steroids

๐Ÿ—๏ธ CD 19 CART rx in SOTs

๐Ÿ—๏ธ Application spectrum of CART rx in SOTRs

#MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

BKVNephropathy post kidney Tx - Dr. Ala Abudayyeh - carefully reduce immunosx gauging risks/benefits - Use of CTLs (from the available data) reduces viremia, no improvement in BKVN - not recommended to use fluoroquinolones, leflunomide, cidofovir #MSKOncoNephCME American Society of Onconephrology

BKVNephropathy post kidney Tx - Dr. Ala Abudayyeh
- carefully reduce immunosx gauging risks/benefits
- Use of CTLs (from the available data) reduces viremia, no improvement in BKVN
- not recommended to use fluoroquinolones, leflunomide, cidofovir
#MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

VEGFi in Oncology Sandra Herrmann MD, FASN: - time of onset of HTN & proteinuria - Renal adverse events - TMA post intraocular Bevacizumab is a possibility - Monitoring & Rx of HTN (ACEi/ARB) and proteinuria #MSKOncoNephCME American Society of Onconephrology

VEGFi in Oncology <a href="/HerrmannMd/">Sandra Herrmann MD, FASN</a>:

- time of onset of HTN &amp; proteinuria
- Renal adverse events
- TMA post intraocular Bevacizumab is a possibility 
- Monitoring &amp; Rx of HTN (ACEi/ARB) and proteinuria 

#MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

๐Ÿ“ Should we be satisfied with negative tests for STEC & ADAMTS13 to label as atypical HUS? ๐Ÿ“STEC - doesn't respond to Eculizumab ๐Ÿ“ average recovery โŒ› with Eculizumab: plts 4 days, renal recovery 30 days ๐Ÿ“ not all aHUS respond to Eculizumab #MSKOncoNephCME American Society of Onconephrology

๐Ÿ“ Should we be satisfied with negative tests for STEC &amp; ADAMTS13 to label as atypical HUS? 
๐Ÿ“STEC - doesn't respond to Eculizumab 
๐Ÿ“ average recovery โŒ› with Eculizumab: plts 4 days, renal recovery 30 days
๐Ÿ“ not all aHUS respond to Eculizumab
#MSKOncoNephCME <a href="/onconephsociety/">American Society of Onconephrology</a>
Avinash Rao Ullur, MD DrNB FASN AHSCP-CHS (@thebeaniac) 's Twitter Profile Photo

Transplant associated TMA: ๐Ÿ“ 3-hit hypothesis in development of TA-TMA ๐Ÿ“New consensus criteria ๐Ÿ“ PK-PD/response based Eculizumab dosing for Rx of TA-TMA ๐Ÿ“Narsoplimab can be tried as a second option - trials on the go American Society of Onconephrology MSK CME

Transplant associated TMA:

๐Ÿ“ 3-hit hypothesis in development of TA-TMA
๐Ÿ“New consensus criteria
๐Ÿ“ PK-PD/response based Eculizumab dosing for Rx of TA-TMA
๐Ÿ“Narsoplimab can be tried as a second option - trials on the go

<a href="/onconephsociety/">American Society of Onconephrology</a> <a href="/MSKCME/">MSK CME</a>