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Metanalysis suggests MTX may be effective in knee OA. 6RCTs, 602 pts of MTX vs PBO, showed MTX significantly relieved pain (mean diff −0.44; P 0.0003) knee/hand OA; Functional improved for knee only, but no differences in quality-of-life outcome or adverse events

2025 BSR Guideline for Treatment of Axial Spondyloarthritis The British Society of Rheumatology has published its 2025 Guidelines for the Treatment of Axial Spondyloarthritis (axSpA); addressing axial and extra-musculoskeletal manifestations including acute anterior uveitis,

Make sure to check out the posters! Session starts at 3:30PM #OARSI2025 OARSI #osteoarthritis

Updates on IL-1Ra gene therapy (GNSC-001) on Knee #osteoarthritis - the DONATELLO trial 🧷 Well-tolerated, mild/mod TEAEs 🎯 1x10^13vg ➡️ prolonged IL-Ra at therapeutic levels over 6 mos OARSI #OARSI2025

On pathophysio of OA: FN7-10 👉🏼 OA synovial fibroblasts & articular chondrocytes 👉🏼 ⬆️ MMP, CRTAC1 👉🏼 ⬇️ aggrecan, type 2 collagen ⬇️ ABCC6 transporter 👉🏼 ⬆️ knee calcification, cartilage degradation, synovial inflammation #OARSI2025 OARSI #osteoarthritis

Recommended #Vaccines Before #Rituximab

#Myositis Malignancy screening tool #Rneumatology #BSR25👇Very Helpful!

❗️Gentle reminder to choose wisely re autoantibody testing, interpret results carefully, & correlate clinically #rheumatology

Some of the uses of MSK US in #rheumatology 📍Assessment of structures (eg bones, tendons, synovium, etc) 📍Diagnosis esp early detection 📍Monitor response to tx 📍Image guided procedures

Nailfold capillaroscopy as another “toy” in #rheumatology 📍High neg predictive value for CTD 📍”Active” scleroderma: ~5 capillary density per mm, frequent giants (dimension >50um) 📍 Has predictive value in future organ involvement (ie PAH, ILD, skin)

ATM: SLE lecture by “the Dr Sandra Navarra” 🤩 You know it’s gonna be good #lupus #rheumatology

SGLT2i Pleiotropic Effect Key notes #SGLT2 #CKD #progression Dr. Divya Bajpai 🇮🇳 Suman Behera Subashri Dr Priti MD,FASN🇮🇳 (प्रिति) Dr. Hardik Patel 🩺💉 @

Full read review of Neuropsychiatric SLE. NPSLE criteria includes 12 central & 7 peripheral findings (psych, cognitive, Sz, CVA/TIA, neuropathy, MS-like). NPSLE AutoAbs are many: Abs against APL, LAC, RP, NMDA, NMO/AQP4, EC, SBSN, UCH-L1, TP1, GAPDH, MAP2, U1RNP

Now published simultaneously in AC&R + A&R, the 2024 ACR Guideline for the Screening, Treatment, and Management of Lupus Nephritis See ACR guideline page for resources - rheumatology.org/lupus-guideline DOI link - doi.org/10.1002/acr.25… Download the article - acr.tw/44sRwJM

🚨 New #ACR guidelines for #LUPUS #NEPHRITIS ✅ LINK: doi.org/10.1002/art.43…

This week in A&R EULAR/ACR Risk Stratification Criteria for Development of RA in the Risk Stage of Arthralgia doi.org/10.1002/art.43… EULAR/ACR Classification Criteria for Pediatric CNO doi.org/10.1002/art.43… Tapering TNFi to withdrawal vs continued stable TNFi in RA

Who else is getting stressed out watching “Painkiller” on Netflix? & I’m only on ep 2 #opioidepidemic