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How RNA phase separates. A Nature Chemistry research briefing on our recent article. nature.com/articles/s4155…

A nuclear pore-anchored condensate enables germ granule organization and transgenerational epigenetic inheritance: nature.com/articles/s4159…

Multiphasic condensates formed with mono-component of tetrapeptides via phase separation. doi.org/10.1038/s41467…

Our lab is looking for a PhD student to join us in exploring RNA biology! Details in the announcement. Feel free to reach out with any questions—and please RT!

Blastocithidia nonstop, a trypanosomatid with a non-canonical genetic code, is now genetically tractable! In this work, with the Yurchenko lab in Ostrava, we successfully modified B. nonstop by tagging its endogenous catalase gene and knocking it out. onlinelibrary.wiley.com/doi/full/10.11…

Our review article about RNP granule transcriptomics is now open on Polymer Journal! Recent technical advances for the purification and proximity labeling of biomolecular condensates enable the comprehensive identification of inner RNAs. nature.com/articles/s4142…

More than a decade of dedicated research on fluorescent probes has inherently led to much, much better results for all imaging methodologies:

Selective RNA sequestration in biomolecular condensates directs cell fate transitions: biorxiv.org/content/10.110…

Sequence-encoded intermolecular base pairing modulates fluidity in DNA and RNA condensates: nature.com/articles/s4146…

Solid phase transitions as a solution to the genome folding paradox: nature.com/articles/s4158…

Sharing our latest work University of Zurich tracking DNA damage inheritance by Live+QIBC nature.com/articles/s4158…. Huge congrats to Andreas Panagopoulos, M. Stout and all co-authors for this tour de force! Beautifully summarized by Sarah Aitken and E. Reilly Nature News & Views nature.com/articles/d4158….

Probing condensate microenvironments with a micropeptide killswitch: nature.com/articles/s4158…

Check out a technology feature in nature by Elie Dolgin regarding our recent 'Killswitch' publication nature.com/articles/d4158… Thank you for the comments and first impressions Richard Young Isaac Klein Danfeng Cai Josh Riback Denes Hnisz Yaotian Zhang

Latest work on RNA condensation from the Banerjee lab, led by a superstar graduate student, Tharun Mahendran. Biomolecular condensates can enhance RNA percolation, leading to the emergence of multi-phasic RNA condensates. nature.com/articles/s4155…

More than 2700 3′UTRs are highly conserved. These 3′UTRs are essential components in mRNA templates, as their deletion decreases protein activity without changing protein abundance. Highly conserved 3′UTRs help the folding of proteins with long IDRs. biorxiv.org/content/10.110…

Our new work bioRxiv 🔗biorxiv.org/cgi/content/sh… BRD4-NUT forms liquid-like condensates that locally constrain nucleosomes via bromodomain-mediated crosslinking: physical control of #chromatin by #LLPS transcription condensates. Adilgazy Semeigazin, MSc Katsuhiko Minami Masa A. Shimazoe

Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior. Congratulations Jing! Happy to have contributed in a small way to this interesting work! nature.com/articles/s4146…

#AcademicTwitter😆#phdlife #phdvoice

The universe is a giant cell made of #condensates

Happy to share our community note published in Nature Communications. In this 14-page article (34 authors from 9 countries), we discuss current practices in biomolecular phase separation and hope it will be useful to the biomolecular condensate community. nature.com/articles/s4146…