Our work is finally out in Nature Physics! Congratulations to all the authors and thanks for the incredible mentorship and leadership from the PIs. Special thanks to Wade Borcherds and Sam Cohen for driving this work especially in the latter stages.

Almost 2 weeks late in posting this! Had an amazing time at IDP GRC hanging out with such a diverse community at les diablerets. Grad student Tharun Selvam Mahendran and I attended and presented our work on the engineering metastability of IDP condensates. 🙏🙏🙏to the organizers.

RNA-driven phase transitions in biomolecular condensates: Molecular Cell cell.com/molecular-cell…

Out today in Molecular Cell Our review article highlights recent advances in ribonucleoprotein condensate biology, focusing on RNA-driven phase transitions. Efforts led by Gable Wadsworth and Sukanya Srinivasan. authors.elsevier.com/a/1jt7A_Oylrla…

Check out our latest work on BioRxiv "The human RAD52 complex undergoes phase separation and facilitates bundling and end-to-end tethering of RAD51 presynaptic filaments" From the Ha lab Taekjip Ha and the Spies lab Maria Spies, PhD (she/her) A summary thread (1/n) biorxiv.org/content/10.110…

Biomolecular Condensates Can Enhance Homotypic RNA Clustering doi.org/10.1101/2024.0…

How it may be possible to maintain integrity of the blood brain barrier that is dysregulated during aging nature.com/articles/s4158… nature Carolyn Bertozzi Stanford Medicine nature.com/articles/d4158…

The Critical Role of the 2'-OH group in Phase Separation and Percolation Transitions of RNA doi.org/10.1101/2025.0…

New preprint in collaboration with Jerelle A Joseph!! We show that the 2’-OH group of ribose sugar plays a crucial role in RNA condensation, while its absence in DNA inhibits phase separation and percolation, a transition linked to condensate arrest. 1/2 biorxiv.org/content/10.110…

Decoupling Phase Separation and Fibrillization Preserves Activity of Biomolecular Condensates doi.org/10.1101/2025.0…

Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation doi.org/10.1101/2024.0…

Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation: Molecular Cell cell.com/molecular-cell…

Latest work on RNA condensation from the Banerjee lab, led by a superstar graduate student, Tharun Mahendran. Biomolecular condensates can enhance RNA percolation, leading to the emergence of multi-phasic RNA condensates. nature.com/articles/s4155…