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This idea is very interesting, but did anyone try to check such hypotheses (re: HP1a) with nucleosome maps? More generally, looking for publications where NRL changes are shown for local regions enriched with certain proteins (excluding studies regarding gene bodies & TF binding)

📢 The 2025 Biophysical Society Annual Meeting in LA is around the corner, and we need nominations/self-nominations for 5 leadership positions for the Multiscale Genome Organization Subgroup This is a fantastic opportunity to support our field and engage with the Society. 🧵⬇️

Dear friends, please reply if you know a neurosurgeon in Romania (or close contacts among medical doctors in Romania who may connect with neurosurgeons). This is for a medical emergency, not for academic research.

some statistics about mass migration of scientists, specifically for our field: ▶️~30% of our followers created accounts on bluesky (most of them stay on both platforms) ▶️~0.8% of our followers deleted accounts on X ▶️likely there will be sizable fractions on both platforms

Hope to see some of you in Hong Kong next year! Circulating Nucleic Acids in Plasma and Serum, 14th CNAPS International Symposium. Hong Kong, December 3-5, 2025. cnaps2025.org. #SNAPS2025 #cfDNA #liquidbiopsy

Interesting preprint on nucleosome spacing from cfDNA [Johnston et al., 2024] biorxiv.org/content/10.110…. The authors refer to NRL changes 10n -> 10n-5 bp. Earlier we showed that NRL decrease in cancer is more complex & context-specific [Jacob et al., 2024] link.springer.com/article/10.118…

Thank you very much Pancreatic Cancer UK for supporting our research! In collaboration with Andrea Mohr, Ralf Zwacka and Greg Brooke, we are developing a new generation of liquid biopsies for early cancer detection based on the analysis of cell-free DNA 🧬

Happy New Year! 2024 was not easy, but despite many challenges we also achieved a lot. We've got grants, published papers, have new exciting findings. This would not be possible without support of friends and collaborators. Wishing you health, happiness, peace & success in 2025!

Low quality picture but… Had to show the matching glasses 🤭🤓

So excited for the festival and this great opportunity to present my research 😄

2nd time at #FOG2025 (1st time presenting!), it never disappoints!✨ Great talks, groundbreaking research and good times with old&new friends Huge thanks to everyone who stopped by my poster, truly grateful for the interest & discussions Already looking forward to next year!🙌

Early detection of #PancreaticCancer saves lives. Teif Lab School of Life Sciences, University of Essex are using cutting-edge technology to measure fragments of tumour DNA in the blood. This "liquid biopsy" could provide an accurate & affordable new test for pancreatic cancer: bit.ly/3F3vXF1

Very happy to contribute to this paper about cfDNA in SCLC, led by the team of Anish Thomas. It's already online in Genome Medicine: Takahashi et al., Genomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor genomemedicine.biomedcentral.com/articles/10.11…

We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to work on the development of new methods for cancer diagnostics related to nucleosomes, chromatin and more jobs.ac.uk/job/DMK060/sen…. Apply by 21st April 2025!