Thrilled to share the final version of my postdoc project, out today in nature! We investigated the Bil system – a ubiquitin-like antiphage defense system – and discovered a new defense mechanism! More info in the thread below 👇 nature.com/articles/s4158…

Nature research paper: A eukaryotic-like ubiquitination system in bacterial antiviral defence go.nature.com/3SzNqc7

Happy to see our paper out @nature today: A bacterial immune system conjugates ubiquitin-like proteins to phage tails. This generates non-infective virions Congrats Jens Hör & Sharon Grayer Wolf! Link to paper: tinyurl.com/Isg15 Read the thread: x.com/SorekLab/statu…

Happy Birthday, Rosalind Franklin! We celebrate her work and influence in science. Thanks to her, we have the historic Photo 51, which revealed that DNA has a double-helical structure!

26 juillet 2024 🇫🇷 July 26, 2024 #Paris2024 Notre protéine favorite se pare des couleurs des Jeux Olympiques ! 🤩 Vive les Jeux ! ✨ #Olympics2024

I am pleased to share my work on Global regulation via modulation of ribosome pausing by the ABC-F protein EttA, which I carried out in BoelLab laboratory. Congratulations to all the authors. nature.com/articles/s4146…

Very happy to announce that our paper “Global regulation via modulation of ribosome pausing by the ABC-F protein EttA” has been published nature.com/articles/s4146…. Congratulation to all the lab members and especially the first authors @ousalemF CNRS 🌍 @IBPCF Université Paris Cité Emily Moore

The missing rRNA Dihydrouridine synthase family has finally been found | PNAS pnas.org/doi/10.1073/pn…

Ok! This is a special one! My last postdoc / first PI paper is out! 🥳 Stay with me if you are into: Defense Systems🛡️ Asgard Archaea⚡️ Origin/Evolution of Immunity💪🏽 rdcu.be/dPyF4 🧵(1/8)

Finally out! 🥳

I am very happy to present our last preprint on #rRNA 2’O-methylation #epitranscriptomic #ribosome. In addition of deleting some #snoRNA We reproduced human methylation pattern in yeast by inducing met at sites that are not usually methylated in yeast biorxiv.org/content/10.110…

bioRxiv: The ubiquitin-proteasome system regulates the formation of specialized ribosomes during high salt stress in yeast dlvr.it/TBzKck

The Last Universal Common Ancestor of Ribosome-Encoding Organisms: Portrait of LUCA link.springer.com/article/10.100…

How to repurpose a #tRNA enzyme into a global stress sensor? Co-led by Bou-Nader lab, Swati Gaikwad, Soheila Bahmanjah, w/ Alan Hinnebusch lab, in PNASNews, we describe how stress kinase Gcn2 adopts and molds Histidyl-tRNA synthetase as a regulatory hub. bit.ly/3YQbiMk

ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site | Nucleic Acids Research | Oxford Academic academic.oup.com/nar/advance-ar…

🧵 Exciting new findings on bacterial stress response regulation, driven by small proteins (≤50 amino acids). Big shoutout to the amazing team behind this work led by Sangeevan Vellappan (Sangeev). Read the full study here: biorxiv.org/content/10.110…

Check out our latest preprint! By investigating translation initiation kinetics in live E. coli cells we found that the IF2α isoform directly interacts with the transcription factor NusA, suggesting a novel link between transcription and translation. biorxiv.org/content/10.110…

Happy to share our little discovery with Simone Mattei team on how ribosomes hibernate upside down on mitochondria during cellular stress is now out Nature Communications! A collaboration between @medicineUVA, @EMBL, EMBL Imaging Centre, MEMC. Congrats to all authors! nature.com/articles/s4146…

The paper was published in nature and can be downloaded here: nature.com/articles/s4158…