Product update: PoET-2 now supports structure inputs for enhanced prediction and design via Python APIs. Check out our new inverse folding tutorial to see it in action. 🔗 docs.openprotein.ai/walkthroughs/P… Sign up for OpenProtein.AI: openprotein.ai/early-access-f…

🚨ICML Paper Alert🚨 What if finding the right protein homologs wasn't a slow search, but a learned part of the model itself? We introduce 𝐏𝐫𝐨𝐭𝐫𝐢𝐞𝐯𝐞𝐫, an end-to-end framework that learns to retrieve the most useful homologs for self-supervised reconstruction! (1/12)

Product update: Indel Analysis lets you score insertions/deletions across your sequence using PoET-2. You can now also compare multiple 3D structures in Mol* to evaluate design alternatives. Sign up now: openprotein.ai/early-access-f…

CASP is getting cut by NIH... 😢 (Anyone with extra funds wanna help support perhaps the most important competition of the century?) science.org/content/articl…

Boltz-1 & Boltz-2 now live via GUI & APIs! Predict protein, protein–RNA/DNA/ligand structures with confidence scores & binding affinity metrics for virtual screening. Compare finetuned models in the new overview page to find your best performer fast. openprotein.ai/early-access-f…

Understanding Protein Function with a Multimodal Retrieval-Augmented Foundation Model 1. PoET-2, a new protein language model, achieves state-of-the-art performance in predicting the effects of mutations on protein function, especially for challenging cases like

Repeat after me: learning from data is only possible by making assumptions.

Nice article about Bonnie Berger Lab 's new work on interpreting PLMs! news.mit.edu/2025/researche…