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Very happy to have the first version of the manuscript from my PhD work in Bigas/Espinosa Lab out!We identify a novel function of the classical NF-κB inhibitor IκBα in regulating pluripotency heterogeneity in mESCs HMar Research Institute Josep Carreras Leukaemia Research Institute (IJC) bioRxiv Cell Biology #pluripotency #development

Time to share my PhD work where we quantified the translational readthrough of thousands of pathogenic stop codons and trained predictive models to predict drug-induced readthrough of any stop codon. With the priceless guidance from Fran Supek +Ben Lehner! biorxiv.org/content/10.110…

New preprint from the lab: Deep indel mutagenesis reveals the impact of insertions and deletions on protein stability and function. First paper from Magda with @ToniBeltran13 biorxiv.org/content/10.110…

Excited to finally share some of my PhD work on quantifying the effects of indel mutations on protein stability and function using deep mutational scanning. From sunny Centre for Genomic Regulation (CRG) together with @ToniBeltran13 and guidance from Ben Lehner biorxiv.org/content/10.110…

Very happy to share what I've been working on in Barcelona with Ben Lehner ! We made many (>400k) mutations in a disordered peptide and the globular domain it interacts with to gain a comprehensive map of how specificity is encoded in a partially fuzzy protein interaction (1/n)