One of our key findings is that transmembrane domain choice is highly consequential for MESA receptors, and we used a number of strategies in this study to systematically examine why. See more details here: biorxiv.org/content/10.110…

Check out SPORT - a computational protein design strategy for making split proteins work for you! Northwestern CSB Northwestern Engineering @VatsanRaman UW–Madison @NatureChemBio nature.com/articles/s4158…

Very excited that our preprint is out! Check out how we engineer vesicles to help fight COVID-19. Thanks to Josh Leonard and Kamat Lab for the mentorship and congrats to the entire team!

Congrats, Neha!

Happy to share that our study on engineering nanoscale decoys to fight COVID-19 is now published! A big thank you to the team for your hard work, advice, & mentorship! (Josh Leonard Kamat Lab Devin Stranford Roxi Mitrut )

Scientists develop ‘decoy cells’ to trick Covid-19 away from healthy ones telegraph.co.uk/news/2022/04/1…

Congratulations to Dr. Neha P. Kamat, from Northwestern, winner of the 2022 ACS Synthetic Biology Young Innovator Award! The award recognizes an outstanding early career investigator conducting research in any area of #SyntheticBiology. Read more: go.acs.org/Ur

Decoy particles have seen preliminary success with HIV. Now, researchers have figured out how to fit them with ACE2 receptors to trick and inactivate SARS-CoV-2. Kamat Lab Josh Leonard Northwestern Northwestern CSB Northwestern Engineering CLP ow.ly/FWi150IPyEP

Bacterial microcompartments undergo dynamic cluster formation that is regulated by substrate turnover. We show that this is a robust mechanism to direct and locally enhance chemical activity. Charlotte Abrahamson Jaime Agudo-Canalejo Ramin Golestanian Tullman-Ercek Lab Kamat Lab biorxiv.org/content/10.110…

Pumped that this is out and honored to have been part of the team! Awesome work, Justin & all!

I’m excited to announce our latest work: a collaboration with Bagheri Lab developing an agent-based computational testbed to explore how tunable CAR T-cell features and tumor properties impact solid tumor treatment Frontiers frontiersin.org/articles/10.33…

What a small world, Bob “Farmer” Hines ! Brother from the CTF (& BU!) doing experiments with colleagues from Northwestern CSB . So so cool - congrats all!

Psyched this project is out! If you're into #SynBio, #ExtracellularVesicles, or #biomembranes, this is for you! So fun working with Justin Peruzzi ; thanks & congrats to an awesome team! Hailey Edelstein Kamat Lab Josh Leonard Institute for Protein Design Peilong Lu

Such a fun project and collaboration! Congrats to all the creative, diligent, and hard-working scientists on the team! #synbio

Excited our latest #syntheticbiology paper is out! See how we build biosensors for use in red blood cells to support in vivo, living diagnostics. Awesome collaboration & awesome team: congrats Taylor Dolberg, Te, Kelly, John, and Josh Leonard #synbio

Very happy to share our work, led by Justin Peruzzi, together with Jan Steinkühler @steinkuehler.bsky.social, Timothy Vu, Taylor Gunnels, Vivian Hu, Peilong Lu, and David Baker that is now out in Nature Communications tinyurl.com/4x47dyde tinyurl.com/44cwfypf

Happy to share our latest paper! So fun co-leading with Justin Peruzzi and so rewarding to work with a group of great people and scientists. Congrats all! Check it out if you’re into extracellular vesicles, biomembranes, or biologic drug delivery! #synbio

The advances produced by Professors Neha Kamat and Josh Leonard “get us one step closer to the ultimate goal of targeted biological drug delivery.” Kamat Lab Josh Leonard Northwestern CSB Northwestern Chemical & Biological Engineering Northwestern University - Biomedical Engineering spr.ly/6013iWJ91