[2:3]
Myelination
Cocultures of oligodendrocytes and Salidroside-treated M1 microglia resulted in increased oligodendrocyte differentiation.

Myelin oligodendrocyte glycoprotein antibody associated disease

#neuroTwitter

youtu.be/-78PEWfUc1Y?si…

BRG1's functions for #oligodendrocyte -precursor cell (OPC) differentiation in the postnatal brain and during #remyelination remain elusive.

Scientists show that Brg1 loss impairs OPC differentiation in the brain with a lesser effect in the spinal cord.

bit.ly/4dckO18

Join us and Dr. Rana Fetit, University of Edinburgh, on May 16th to learn expert level tips for iPSC/hESC to oligodendrocyte differentiation.

All attendees will receive a certificate of attendance and recording of the full webinar.

Register: ow.ly/gWA450RvaIx

Image-based screening demonstrates that environmental compounds including quaternary compounds and organophosphate flame retardants alter oligodendrocyte development.

buff.ly/3Vy7622

#highcontentimaging #toxicology #screening

A gene therapy injected injured woman’s diagnosis in Australia called MOGAD or Mylelin Oligodendrocyte Antibody Associated Disease. Anyone in America get this diagnosis? #mogad

[2:3]
Myelination
Cocultures of oligodendrocytes and Salidroside-treated M1 microglia resulted in increased oligodendrocyte differentiation.

nature.com/articles/s4159…

Some patterns were cell type-specific and localized to distinct spatial domains, such as an oligodendrocyte-specific pattern mapping to WM.

However, others were not cell type or domain-specific, including a transcriptional signature associated with synaptic structure/function.

Reserve your place at our free online workshop.

Tips & tricks for iPSC/hESC to oligodendrocyte differentiation. May 16th, 2024

ptglab.com/news/events/ti…

#phdchat #STEM #phdlife

BRG1 programs PRC2-complex repression and controls #oligodendrocyte differentiation and remyelination, say Jiajia Wang, Qing Richard Lu and colleagues Cincinnati Children's: hubs.la/Q02tPny-0

#Development #Neuroscience #Chromatin #epigenetics

cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons:nature.com/articles/s4159…

Open Access UCL Research: Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors discovery.ucl.ac.uk/id/eprint/1018…

biorxiv.org/content/10.110…

'In contrast, the presence of CARNS1 and endogenous HCDs does not protect against cuprizone-induced demyelination, and is not required for normal oligodendrocyte precursor cell differentiation and (re)myelin to occur.'

The last thing anyone would want to do is contribute to glymphatic system dysregulation and oligodendrocyte insult through a 'bystander' effect. I would want to make sure astrocytes are not productively infected. ncbi.nlm.nih.gov/pmc/articles/P…

M-SparCapital The craniosacral therapy is accelerated by clemastine for oligodendrocyte precursor cell epigenetic transformation into a myelin producing cell.

Giulia Casal Our lab has done some work on this: pubmed.ncbi.nlm.nih.gov/25417154/