Updated #GRIN2A GeneReviews article by my colleagues Vincent Strehlow, Johannes Lemke et al. 👌 👇 Proud that our Institut für Humangenetik 🧬 | Uniklinik Leipzig team has now contributed/written all GRIN GeneReviews articles for #GRIN1, #GRIN2A, #GRIN2B & #GRIN2D. ncbi.nlm.nih.gov/books/NBK38562…

Tweet 1/7: 💡Glad to announce our latest pre-print. In a close collaboration with Steve Traynelis team, we wanted to understand variant function in #neurodevelopmentaldisorder & #epilepsy causing genes #GRIN1, #GRIN2A, #GRIN2B and #GRIN2D! medrxiv.org/content/10.110…

rb.gy/acx6t8 ➡️ De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor.🦠We identified 48 variants in the M3 transmembrane helix across #GRIN1, #GRIN2A, and #GRIN2B in 56 patients. Good Job Johannes Lemke, etc.

Two years ago we (labs: Johannes Lemke, @traynelis, Tim Benke & us) developed grin-portal.broadinstitute.org to provide a curated data home for #GRIN1, #GRIN2A, #GRIN2B & #GRIN2D disorders. We just added a page tracker & were positively surprised by number of users in only 10 days.

Research re #GRIN2A led by investigators from the NHMRC Translational Centre for Speech Disorders was recently published. Prof Ingrid Scheffer ruth braden Lottie Morison Murdoch Children's Research Institute (MCRI)

Today marks the beginning of GRI Disorder month. My granddaughter has GRIN2A. Extremely rare and dibilitating. For more info go to curegrin.org #RareDiseaseAwareness #grin2a #curegrin

We would like to share with you the playlist off all the presentations from our 5th European GRIN conference that was held in Barcelona past October. You can find the full play list here: youtube.com/playlist?list=… #grin #grin2b #grin2a #gria #grin1 #grin2d #NMDA #NMDAR #AMPA

#GRIN2A is associated with a neurodevelopmental and epilepsy phenotypic spectrum. Jeff Kuerbitz leverages extrapolated functional data to predict successful treatment of self-injurious behaviour with memantine. #CNSAM #PrecisionMedicine 💊 #PatientCenteredCare

Read our new article rdcu.be/dmXlt about the topic: Loss of #Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons. 🫂 Great work by Johannes Lemke, Ilona Krey and many others...

GRIN2Bsyndrome We investigate potentially recognisable features of #GRIDisorder with a facial recognition tool. #GRIN1 #GRIN2A #GRIN2B #GRIN2D #GRIA1 #GRIA2 #GRIA3 #GRIA4You can support our research with a photograph - we would be very pleased.

Research opportunity for #GRIN1 #GRIN2A #GRIN2B #GRIN2D #GRIA1 #GRIA2 #GRIA3 #GRIA4 families!

We investigate potentially recognisable features of #GRIDisorder with a facial recognition tool. #GRIN1 #GRIN2A #GRIN2B #GRIN2D #GRIA1 #GRIA2 #GRIA3 #GRIA4 You can support our research with a photograph.  This is how: uniklinikum-leipzig.de/einrichtungen/… CureGRIN GRIN2Bsyndrome Thanks you!

Have a look at our 2022 achievements on #GRIN1 #GRIN2A #GRIN2B #GRIN2D #GRIA1 #GRIA2 #GRIA3 #GRIA4: uniklinikum-leipzig.de/einrichtungen/… Thanks to the research groups of Tim Benke, Steve Traynelis and Dennis Lal Join our registry grin-portal.broadinstitute.org CureGRIN GRIN2Bsyndrome

MECP2 and TSC2 were the most frequent genes identified; GRIN2A and SCN1B were the second most common genes. #scn1b #grin2a #seizures #epilepsy

We’re super proud of Macsen’s progress since November so we’re treating him to a new pop to celebrate every time he invites a new Disney friend #TeamMacs #GRIN2a