Umbrella-shaped antibacterial toxin particles drifting toward and engaging a bacterial target cell. The toxins are derived from Streptomyces and potently inhibit the growth of competing species in the same genus.
Credit: Angela Gao

Nature research paper: Streptomyces umbrella toxin particles block hyphal growth of competing species go.nature.com/3UlBQ5z

B356 - Come chat Streptomyces #Microbio24

Streptomyces umbrella toxin particles block hyphal growth of competing species nature.com/articles/s4158…

Streptomyces umbrella toxin particles block hyphal growth of competing species.
nature.com/articles/d4158…

Azoxyl compounds are a group of natural toxins. Interested in their biosynthesis? Here comes our recent work. pubs.acs.org/doi/10.1021/ac…

We discovered that in Streptomyces pyrroloquinoline quinone(PQQ) enhances natural products metabolism and turns on silent BGCs. Add PQQ or express its BGC in your strain and harvest lots of molecules! nature.com/articles/s4225… #Streptomyces #Naturalproducts

Recruiting a #ComputationalBiologist or #MetabolicModeller PDRA to join the Systems Microbiology Group Surrey Biosciences. Collaboration with Paul Hoskisson 😷🔬🧫🧬🐸🐍🦎 and GSK to improve #streptomyces fermentations #metabolic_modelling & #engineering_biology Biotechnology and Biological Sciences Research
tinyurl.com/5fb7fxx4

So excited to see this amazing story from #proudofalumni Joseph Mougous ⁦University of Washington⁩ finally out in print, discovery of a new family of “umbrella toxins” with combinatorial components including #glycotime lectin domains
nature.com/articles/s4158…

Our paper on access to pepticinnamins by inactivation of the azodyrecin BGC. pubs.acs.org/doi/full/10.10…

Great week at #Microbio24 so far. Thank you Microbiology Society for allowing me to present my work regarding Streptomyces bldA mutants, and to everyone who stopped by to chat about it.

S is for Streptomyces griseus! 🧫

Did you know that Streptomyces bacteria secrete antibacterial protein toxins (in addition to antibiotics) to compete among related species? Check out our article with the Mougous lab describing these findings!

HHMI NEWS
UW Biochemistry

nature.com/articles/s4158…

MtrA - a highly conserved response regulator - has now been shown to directly control production of the primary antibiotics (and development) of S. avermitilis, S. coelicolor, S. formicae and S. venezuelae. MtrA also controls the cell cycle in TB.

link.springer.com/article/10.118…

Fall in love ❤️
Endophytic Actinomycete isolat on International Streptomyces Project 2 (ISP2) medium. I have isolated it from medicinal plants, and we can see their special colony's aspect 😍 with the presence of pigmentation.

ε-Polylysine hydrochloride is a natural polymer consisting of multiple lysine molecules linked together. It is produced by certain strains of bacteria, including Streptomyces albulus.

New Research: Description of Streptomyces naphthomycinicus sp. nov., an endophytic actinobacterium producing naphthomycin A and its genome insight for discovering bioactive compounds frontiersin.org/articles/10.33… #microbiology

» Streptomyces umbrella toxin particles block hyphal growth of competing species | Nature nature.com/articles/s4158…

Go chat Streptomyces regulation and antibiotic production at poster #356 with Kelly #MicroBio24

A membrane-like structure envelopes substrate mycelium during colony development in Streptomyces eurekamag.com/research/008/0…