📢 #CancerResearch Spotlight➡️JNCI: Pre-Diagnostic Plasma #Proteomics Profile for #HepatocellularCarcinoma , feat. senior researcher Towia Libermann, BIDMC. Proteins detectable in blood could improve predictions about #LiverCancer risk➡️Medical Xpress: bit.ly/3Wpk3M1

Thank you to JNCI for publishing our editorial on Genomic Risk Scores in #ProstateCancer

Arnab Basu UAB Urology O'Neal Comprehensive Cancer Center at UAB UAB Heersink School of Medicine UAB Medicine

See full article at: academic.oup.com/jnci/article-a…

JNCI Division of Cancer Sciences Manchester Cancer Research Centre Christie Library The Royal College of Radiologists ESTRO #ESTRO24 UCL Comprehensive Clinical Trials Unit #WhereisHoskin academic.oup.com/jnci/advance-a…

📑💊
Differences of CDK4/6 inhibitors
JNCI

✅Preclinical

✔️Affinity to different CDKs
✔️Different effects on senescence and apoptosis
✔️These differences may affect efficacy, side effects and resistance

✅Clinical

➡️Metastatic
✔️Only ribociclib plus letrozole…

12〜13歳の時にHPVワクチンを接種した女性は子宮頸癌発生率はゼロであった．14〜22歳の時の接種者は未接種者と比較して有意に子宮頸癌発生率が低かった（10万人あたり3.2人vs8.4人）．スコットランド公衆衛生局研究（JNCI 2024 Jan.22）

12〜13歳時のHPVワクチン接種者の子宮頸癌発生率ゼロを達成

Excited to share our last publication at JNCI on how low physical function postcancer diagnosis is associated with higher mortality risk in postmenopausal women! Thanks to all co-authors! Christina Dieli-Conwright, PhD, MPH Alexi Vasbinder, PhD, RN academic.oup.com/jnci/advance-a…

💊Metformin and anti-tumor immunity in pancreatic cancer
JNCI

✅Metformin use was associated with -OS⬆️
-pro-tumoral immunity⬇️
-anti-tumoral immunity⬆️

➡️Samples from PREOPANC RCT
➡️up-front surgery and nCRT-treated patients
➡️Transcriptomic NanoString immunoprofiling…

🦠Un estudio publicado en JNCI indica que no se registraron casos de cáncer cervical invasivo en mujeres vacunadas a los 12-13 años con la vacuna bivalente contra el virus papiloma humano (VPH)
💉Estos resultados reflejan la eficacia de los programas de vacunación contra el VPH

Munson et al. Antineoplastic Activity of Cannabinoids, JNCI: Journal of the National Cancer Institute, Volume 55, Issue 3, September 1975, Pages 597–602.
doi.org/10.1093/jnci/5…

#WhereisHoskin presents #SCORAD QoL data. No difference between 20Gy in 5# or 8Gy in 1#. Patients want to be looked after at home. Paper now published in JNCI UCL Comprehensive Clinical Trials Unit RTphysics Manchester ESTRO Division of Cancer Sciences Manchester Cancer Research Centre #TeamManchester

❓Sequence of radiotherapy and immunotherapy is an important debate
JNCI

⁉️Most immunoradiotherapy randomized trials in advanced stage > disappointing results
✅ When immunotherapy was delivered on top of gross disease elimination with curative-intent radiotherapy >…

コロンビア大での仕事、米国立がん研究所の機関誌(JNCI) に掲載されました。

若年者の子宮体癌前病変に対する黄体ホルモン治療に関して、経口薬と子宮内放出型ホルモン薬の治療効果を示した質の高いエビデンスを目指しました。

ホルモン放出型IUDが今後大きな選択肢になっていく上で重要な報告です。

Sharing about an article just published in JNCI looking at air pollution - fine particulate matter - and breast cancer risk. academic.oup.com/jnci/advance-a…

TP53-associated early breast cancer

227 pts, mFU: 70 mo

mAge➡️37
HR+/HER2-➡️40.9%
HR+/HER2+➡️34.4%

5y RFS (HR+/HER2)➡️61.1%!!
5y radiation-induced sarcoma➡️4.8%‼️

Quite an informative analysis. Congrats to all the researchers

OncoAlert JNCI
academic.oup.com/jnci/article-a…

Happy Birthday to our amazing MD/CEO Clare Omatseye. We are grateful for your inspirational leadership and wish you many happy returns.

#JNCI #TeamJNCI #PeopleofJNCI

Published in the JNCI, Dr. Albert Farias and his team identified major themes and subthemes that highlight exposure to racial discrimination and its consequences for Black cancer patients when receiving cancer care. Read the full publication here:
uscnorriscancer.usc.edu/2023/10/18/stu…

Physical activity & checkpoint inhibition: association
with toxicity & survival
JNCI
doi.org/10.1093/jnci/d…
🇩🇰 RWD, 251 pts
Higher physical activity levels at the start of ICI treatment:
👉 lower risk of severe irAEs
👉 probably longer survival
😅'easy' to implement…

🎙PBI ✖️WBI for early-stage #breastcancer : JNCI
📌Metanalysis:17,234 👥➡️14 RCTs & 6 observational
- 🥇endpoints: IBR,cosmetics & AEs
📊Findings:
👉5y IBR: PBI = WBI (RR 1.34, 95% CI 0.83—2.18)
👉10y IBR: PBI = WBI (RR 1.29, 95% CI 0.87—1.91)
👉Cosmesis:Insufficient…

I’m very excited to present our finding that diet quality is associated with ovarian cancer survival, but not ovarian cancer risk at #ASPO2024 American Society of Preventive Oncology (ASPO) Melinda irwin Yale School of Public Health Yale Chronic Disease Epidemiology Department

This study is published in JNCI, check it out: track.smtpsendmail.com/9032119/c?p=Lz…

A study from Tim J Palmer and colleagues at Public Health Scotland finds NO cases of #cervicalcancer in fully #vaccinated young women.

Read the paper in JNCI bit.ly/3ONYD6W
Listen to the first author Tim J. Palmer in this video.

Public Health Scotland