🔥Years in the making, now published! My final postdoc project in Nature Communications shows that Tau and TSPO PET follow gradients🌈 of connectivity in #Alzheimer disease 🧠 nature.com/articles/s4146… Thanks to Alzheimer's Association Sunnybrook Health Sciences Centre McGill Research Centre for Studies in Aging Now ready for new adventures!🌍☺️

Douglas Neuroinformatics Platform has announced its first software product, OpenDataCapture. Read more about it at this HackerNews post: news.ycombinator.com/item?id=410371…

Harmonizing tau PET in Alzheimer’s disease: The CenTauR scale and the joint propagation model A first step towards a Centiloid equivalent for Tau PET. Great to see this published; I really enjoyed the discussions with the Working Group (and look forward to the next steps).

Why do some with #Alzheimer's pathology have more language or visual issues than memory problems? In a new paper led by Stefanie Piña & Renaud LaJoie, we explore if more copathology explains #AtypicalAlzheimer. tinyurl.com/mu8dtzts See comments 👇 UCSF MAC Global Brain Health Institute Atypical Alzheimer's Disease PIA

The Multimodal Neuroimaging Lab DZNE Research Center Anne Maass is getting ready for Alzheimer's Association #AAIC24! 🎉 Please drop by for a chat if you are interested in multimodal research on successful aging, early AD and memory.

Excited for #AAIC2024 and #AIC2024! Don't miss the work of the Genetic NeuroEpidemiology and Biostatistics team (Barcelonaβeta Brain Research Center)👇! Alzheimer's Association Pati Blanca Rodríguez-Fernández 🏳️‍🌈🧬🧠 armand_age Federica Anastasi Tavia Evans

The median time interval between becoming Tau PET positive and developing dementia is ~7 years and no T+ participant remained dementia-free after 15 years.

A major first, preliminary evidence from Autosomal Dominant AD that primary prevention with anti-anyloid therapies may decrease the risk of cognitive decline. The sample is modest but gives hope. Read the preprint. Randall Bateman #AAIC2024 #ENDALZ papers.ssrn.com/sol3/papers.cf…

Very emotional moment to see the Brazilian neurologist who gave my father’s AD diagnosis, 20 years ago, being now granted such an honorable international prize. Very well deserved 👏🏻

It was pleasure to present our head-to-head comparison between plasma p-tau217 and Tau-PET for predicting future cognitive decline in >1500 cognitively unimpaired individuals from 9 cohorts. #AAIC24

Lecanemab attenuates the rate of tau (PET) accumulation. #AAIC24

Current projections estimate 153 million people will be living with dementia by 2050. Nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors starting in childhood, suggests new report from a standing Lancet Commission: buff.ly/46nvoPR

Quand on parle de maladies graves, comme les crises cardiaques, les AVC ou les cancers, l’art de la prévention les repousse mieux que la médication et même, tenez-vous bien, les dépistages. La prévention n’est pas ketchup lactualite.com/sante-et-scien…

A paper from the PREVENT-AD Research Group finds that changes in cortical rhythms in #Alzheimer’s are organized along neurochemical boundaries, and the strength of these alignments is related to clinical symptom severity. buff.ly/3WRnY45 The McConnell Brain Imaging Centre (BIC) Douglas Research Centre

🚢 Anchors away! The #HAI2025 Conference is mooring at the "Rich Port" (aka San Juan, Puerto Rico) on Jan 15-17, 2025. Get ready for some serious brainwaves and Caribbean vibes—sun, science, and breakthrough discoveries await! 🌞🧠

Integration of FDG-PET and omics at the biological process level 👉 insights about FDG-PET biological interpretation in #alzheimers and a new method to integrate these different modalities! Stellar work led by Guilherme Povala Pascoal Lab and #MarcoDeBastiani Zimmer Lab 🌟

Happy to share our new paper in Nature Neuroscience from the BioFINDER ‼️ We looked at Olink Proteomics in relation to Abeta and tau-PET across the #Alzheimers continuum, and compared to patients with non-AD neurodegenerative diseases! nature.com/articles/s4159…

This is one of the most exciting papers I can remember being a part of. The addition of tau-PET really helped to define which proteins respond early in the AD process vs. those that are associated with later phases. A small thread with a few highlights:

A heartfelt thank you to participants from the PREVENT-AD cohort at the Centre for Studies on Prevention of Alzheimer’s Disease for today's event & to Sylvia Villeneuve and team whose leadership is truly paving the way for the prevention of #Alzheimer's disease.

Merci pour votre présence et votre support 😊