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BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and #Immune Checkpoint-Therapy Efficacy by Salmon, Shavkunov, Gubin et al. bit.ly/3turAcm Matthew Gubin MD Anderson Cancer Center Parker Institute for Cancer Immunotherapy

Immunotherapy has revolutionized cancer care - looking forward to even more progress with brilliant team members near and far - thank you @PamSharmaMDPhD @JimAllisonPhD and all MD Anderson Cancer Center and beyond!

Here for the exciting launch of the Allison Institute ⁦MD Anderson Cancer Center⁩. Dawn of a new era in cancer cures for our patients.

Last week I was invited to sign a letter offering support for David Sabatini, organized by current & former lab members. Universities considering hiring him have asked for this. I will not sign. There was no option to provide a more nuanced response, so I will elaborate here 🧵

How do you deal with academic burnout in 3 words or less GO: Mine is 'just keep swimming' literally and figuratively 🥲 #AcademicTwitter #AcademicChatter #phdchat #phdvoice #academicburnout

A fork in the road led us to accept HoustonBaptistU undergrad Daniel Idowu (center) into our lab for 1 yr UPWARDS research program MD Anderson Cancer Center . Malcolm Moses Doctuh Moses was lab mentor w/Diana Machado Genetics&Epigenetics Here at🎓party with mother Grace.

Abortion is not just health care, it is a human right. Beyond infringing on bodily autonomy, there are conditions in pregnancy that result in death without safe abortion care. This is a calling for all in medicine to stand on the side of justice nejm.org/doi/full/10.10…

Comparable tumor immune microenvironment in human glioblastoma & murine model: buff.ly/3OdgOk3 Zamler_Brain @Jianhu_Neural @draettag Amy Heimberger, MD Lurie Cancer Center Malnati Brain Tumor Institute at Northwestern MD Anderson Cancer Center Stephanie Watowich Kunal Rai @tcellsrus Laura Kahn @cinziakas Kristin Huntoon Katarzyna (Kasia) Tomczak

Modeling anti-CTLA-4-mediated intestinal irAEs reveals common immune signatures and the importance of fecal microbiome dysbiosis as irAE-driving mechanisms, enabling preclinical therapeutic interventions. From Zhou, Stephanie Watowich & colleagues MD Anderson Cancer Center: bit.ly/3GcPDoe

Thrilled to share our team science at MD Anderson leading to new ICI colitis models! Work by an outstanding group including Yifan Zhou, Yusra Medik, nadim_ajami, Matthew Gubin, Dr. Patrick Hwu Jennifer Wargo MD

Join us for the IOTOX Clinical Education Symposium on Dec. 3 to better understand the treatment and care of patients with immunotherapy-related toxicities. Register today: fal.cn/3tFKW @Cathy_Ileana_MD Jamie Lin MD FASN @McQuadeMDLAc #EndCancer

World class TRIUMPH mentors are hiring post-doctoral fellows MD Anderson Cancer Center: Jennifer Wargo MD Stephanie Watowich Raghu Kalluri Cullen Taniguchi, MD Peter Van Loo @tcellsrus Wenyi Wang Anil Sood Pawel K. Mazur Li Ma, PhD Albert Koong, MD PhD Scott Kopetz George A. Calin Apply: bit.ly/3hDLMXj

Such incredible, pertinent work from my sister @MarinaWatowich!! Congrats on your PhD defense, Meena, or do I now say, Dr. Watowich?!

Proud to announce our new PhD in the family, Dr. Marina Watowich!! ⁦@MarinaWatowich⁩ ⁦Noah Snyder-Mackler⁩

Selected 📄 for our 5th #CME activity: “Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration” from Zhou, Stephanie Watowich et al. bit.ly/3GcPDoe New CME course MSK CME is available now: bit.ly/3NTG7s7

Outstanding undergrad interested in cancer research? Awesome opportunities MD Anderson Cancer Center for summer research: bit.ly/3C7h3sS, bit.ly/3Q0sVCK. Applications now open! #CancerResearch #summerintern #REU

Excited to share our review on the effects of the microbiome on immune-related adverse events with immunotherapy, great collaboration with Mimi Wang, Rob Jenq, and Jennifer Wargo MD at MD Anderson Cancer Center

Congratulations Matthew Watowich !! Fantastic to see your outstanding review on T cell exhaustion in gliomas in press!

Superb science presented at the Cytokines in Cancer Aegean Conference! Thanks to Belinda Parker ⁦Belinda Parker⁩ and Eleanor Fish for organizing such a terrific meeting ⁦Aegean Conferences⁩