Two consecutive articles on role of microenvironment on Biomolecular condensates, led by Susmita Sarkar SUSMITA SARKAR We report in Biochemistry an interesting observation of salt and temperature-induced re-entrant condensation of Abeta40 pubs.acs.org/doi/abs/10.102… 1/2

In an investigation published in eLife - the journal, we combine simulation and its apt experimental validation (By Dibyendu Das Dibyendu Das's group at IISER-K) to elucidate role of ATP on biomolecular condensations elifesciences.org/articles/99150 2/2

.@krishnanandac et al. from CSIR-IICB report the phase separation of leishmania kinetoplasmid membrane protein. They show with spectroscopy and microscopy that phase separation of this protein depends on solution conditions and presence of cholesterol. pubs.acs.org/doi/full/10.10…

The newest is EMBO Reports We combined parasite biology and biophysics to show that KMP-11 transfers cholesterol and induces membrane phase transition in leishmania. A great collaboration with Budhaditya Mukherjee We thank CSIR-IICB CSIR, India ICMR embopress.org/doi/full/10.10…

FRET correlation functions, a new model-free analysis tool. For dynamics from nano to milliseconds in diffusion-based smFRET experiments. Clean correlation functions, no diffusion component left. Perfect to verify HMM fits. biorxiv.org/cgi/content/sh…

Just Published in PNAS Nexus we use physics based model and experimental data to show how state-switching of ribosome can fluidise the bacterial cytoplasm Palash Bera Wasim Abdul (him/his) took lead, great collaboration and bio-insights from Somenath Bakshi ow.ly/ZTZM50Uj5OL

Kaushiki Chatterjee and I are excited to share our preprint about fate restriction in pluripotent cells! We show that EHMT2 counteracts the reactivation of clusters of totipotency genes by nucleating heterochromatin domains at LINE-1 repeats. Effie Apostolou and Stadtfeld Labs 1/n

facebook.com/share/v/1Amv5q… Contractual staffs of CSIR-IICB , who were working for last 15-30 years, are dismissed abruptly, without any prior notice. CSIR, India HRDGCSIR CSIR-IICB PMO India Dr Jitendra Singh

Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion. -> embopress.org/doi/full/10.10…

Congratulations to Ashmita, who has successfully defended her thesis. Her journey was a difficult one, with many twists and turns; but as they say, when going gets tough, the tough gets going. Ashmita, you are the toughest cookie, and we are really proud of you.

A "project Research Scientist" (aka postdoc) position in the area of computational biophysics is available in the group. Interested candidates can email with a CV. Start date is immediate, open until filled.

Cover from my 2nd author publication "Influence of magnesium ions and crowding agents on structure and stability of RNA aptamers" in collaboration with Dr Ipsita Roy NIPER SAS Nagar (Mohali) Krishnananda Chattopadhyay Sumangal Roychowdhury •°○°•○ CSIR, India AcSIR CSIR-IICB pubs.acs.org/toc/bichaw/64/6

I’m excited to share our latest research from Musser Lab , published today in nature. Using two-color 3D MINFLUX, we directly visualized nuclear import and export events through transport-active nuclear pores. nature.com/articles/s4158…

Outstanding work by Abhishek Sau , Debolina and Ankith (Ankith Sharma) just published in nature !! Congratulations to Musser Lab

Looking forward to sharing our research with the IDP community tomorrow!

The newest one from the lab. Multivalent interaction induces phase separation and formation of more toxic aggregates of α-syn in a yeast model of Parkinson's disease biorxiv.org/content/10.110…

Swiggy Food is now robbing. Ordered today evening four burgers and two fries from KFC (order number .207072574923851). Delivered one burger and one fry. The nice delivery person told me to call the customer service for the refunds. Have been chatting with the customer service for

A new and simple model-free method to analyze smFRET experiments. Protein dynamics from nano- to milliseconds without the nasty diffusion decays in standard FCS experiments - kudos to the great Ivan Terterov! Have a look! nature.com/articles/s4146…

New publication at Biochemistry. Ahana and Dwipanjan studied two #ALS mutants of #SOD1 and showed how their conformational dynamics and stability modulate phase separation behaviors. Many congratulations to them. CSIR, India CSIR-IICB pubs.acs.org/doi/full/10.10…

(1/2) We are excited to announce that our paper, led by PhD student Shiv Rekhi, has been published in PNAS: pnas.org/doi/10.1073/pn…. In this work we compute the transfer free energies of amino acid side chains from the dilute to the dense phase.