A Data Guided Approach To Building An ML Ready Protein Expression Dataset A new project aims to create an openly available and extensible experimental platform and standardized data ontology for collecting soluble recombinant protein expression data across organisms. The

I love the idea of "micropublications" micropublication.org (preparing one now)

Design-Build-Test-Learn guided engineering of a whole-cell pyruvate biosensor based on transcription factor biorxiv.org/content/10.110… #biorxiv_synbio

CF2H: a Cell-Free Two-Hybrid platform for rapid protein binder screening biorxiv.org/content/10.110… #biorxiv_synbio

New instrument, new ribosomes!

Cell-Free Expression of Nipah Virus Transmembrane Proteins for Proteoliposome Vaccine Design | ACS Nano pubs.acs.org/doi/10.1021/ac…

Excited to dive into this book and explore the fascinating connections between organisms, business, and beyond. Curious to see how biology fits into the bigger picture. 🏖️☀️😎🌊

Machine Learning-Guided Evolution of Pyrrolysyl-tRNA Synthetase for Improved Incorporation Efficiency of Diverse Noncanonical Amino Acids Nature Communications Researchers have developed a novel machine learning framework to engineer pyrrolysyl-tRNA synthetase (PyIRS), significantly

New synbio tools 4 the fastest growing bacteria! Check this out! Sebastian S. Cocioba🪄🌷 doi.org/10.1093/nar/gk…

Amphiphilic Copolymers and Their Role in the Study of Membrane Proteins | The Journal of Physical Chemistry Letters pubs.acs.org/doi/10.1021/ac…

Self-assembling protein materials with genetically programmable morphology and size biorxiv.org/content/10.110… #biorxiv_synbio

"high-throughput phage isolation using droplet microfluidics" PRISM: A platform for illuminating viral dark matter biorxiv.org/content/10.110…

International Multi-site Implementation of Local Cell-Free Protein Biomanufacturing to Advance Health and Research Equity medrxiv.org/content/10.110…

Screening de. novo designed protein binders in unpurified lysate using flow induced dispersion analysis biorxiv.org/content/10.110…

Fascinating bacterial process rebuilt in the lab: ATP synthesis driven by atmospheric hydrogen concentrations | PNAS pnas.org/doi/10.1073/pn…

How can we enable biotechnology? Make protein faster!! Check out our new work in cell-free protein synthesis making ~1 g/l/h of protein. Led by the amazing Meagan Olsen Northwestern CSB biorxiv.org/content/10.110…

Rapid Screening of Plastic-Degrading Enzymes Using an Optimized Cell-Free Protein Synthesis Platform doi.org/10.4014/jmb.25…

The test phase of biological design is too slow. How can we accelerate it? We show how cell-free systems can be used to speed up the study of post-translational modifications for RiPPs and glycosylation. Nature Communications nature.com/articles/s4146…

Accelerating Protein Design by Scaling Experimental Characterization 🚀 New preprint from David Baker!🚀 1. This preprint introduces a novel workflow called Semi-Automated Protein Production (SAPP) that significantly accelerates the experimental validation of de novo protein

More than 30% of the world's population lacks access to essential medicines. What if we could make medicines when and where they are needed? Enter #cellfree biomanufacturing. With DeLisa Research Group Matthew DeLisa we show a new approach to portable medicine making. biorxiv.org/content/10.110…