My paper with Amy Whitehead Mike Campbell & Cindy Cooper Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable Has been cited 1000 times doi.org/10.1177/096228…

Just had a paper published led by Holly Tibble with researchers from AUKCAR on using routine data in research

My PhD student is undertaking a DELPHI on reporting of sample sizes with studies with adaptive designs in protocols and grants. Please fill in if you can

Today's date 5-2-25 Is a palindrome

Comparison of statistical methods for the analysis of patient-reported outcomes (PROs), particularly the Short-Form 36 (SF-36), in randomised controlled trials (RCTs) using standardised effect size (SES): an empirical analysis hqlo.biomedcentral.com/articles/10.11…

New Publication 🔊: Trials special series - the collection, analysis and reporting of adverse events in randomised controlled trials by Rachel Phillips & Victoria Cornelius trialsjournal.biomedcentral.com/articles/10.11…

In clinical trials it is not only potential benefits that should be measured - it is crucially important that any potential #harms are also investigated 1/7 #MethodologyMonday #118

Attending an excellent talk by Nikki Totton entitled at #SCT2025 entitled Using benefit risk methods to adjust the non-inferiority margin based on treatment benefits

A great talk by James Salsbury at #sct2025 entitled Assurance methods for designing a survival trial with delayed treatment effects

The protocol for MissionEB - a randomised, double-blinded, placebo-controlled, two-centre, crossover trial - a study to assess mesenchymal intravenous stromal cell infusions in children with recessive dystrophic epidermolysis bullosa has been published doi.org/10.1136/bmjope…

Had a paper published with Laura Flight and Alan Brennan entitled Value-adaptive clinical trial designs for efficient delivery of publicly funded trials - a discussion of methods, case studies, opportunities and challenges doi.org/10.1186/s12874…