So great to have Sallie Permar MD PhD on Case Western Reserve's campus today! Of course we talked babies, dimeric IgA, #breastmilk , and how we need more #pediatricians 👏🏼👏🏼 Thank you to CWRU Biochemistry Department for inviting her to our beautiful campus! Weill Cornell Pediatrics UH Rainbow Babies

Think of the children! No, not those children. No, not them, either. No,

Dad’s gut microbes matter for pregnancy health and baby’s growth nature Jamie Hackett
nature.com/articles/s4158…
Commentary by: Eldin Jašarević Yoel Sadovsky
Dr Liisa Veerus (she/her) BlaserLab
nature.com/articles/d4158…

Super interesting work about the understudied postpartum preeclampsia!

Fantastic summary of the H5N1 situation by the incredibly eloquent Hutchinson Lab theguardian.com/science/audio/…

Absolutely- Immunology is for everyone!!

The health system in #Haiti is on the brink of collapse.

World Health Organization (WHO) is deeply concerned about the impact of violence on hospitals and health centers in the Port-au-Prince metropolitan area, where less than 50% of facilities are functioning at normal capacity. And those that remain…

#Immunology is for everyone! #50YearsofCell focus issue led entirely by my amazing colleague Dr. Cheri Sirois Cheri Sirois 🧬 Feat Ruslan Medzhitov Prof. Akiko Iwasaki Paul G Thomas Marion Pepper Hongbo Chi CarpenterLab Luke O'Neill Jonathan D G Jones LizNeeley shorturl.at/qAPQX

From an immunology point of view, it's not impossible that you could develop an antibody response to milk containing H5N1 antigens. If I could develop immunity by drinking a milkshake?? To a pathogen with pandemic potential that I am seronegative for? I mean.. I'm not against it!

A really great article abt the #H5N1 outbreak in dairy cattle. It summarizes well how the USDA and those involved in agriculture industries must deal with this outbreak
‘You know, we can't go over it. We can't go around it. We can't go under it. We have to go through it.’

USDA scientists weigh avian flu vaccine for cows; virus may be spreading from cattle to poultry cidrap.umn.edu/avian-influenz…

If you are an immunologist attending #AAI this year in Chicago and would like to talk to the microbe.tv #Immune team, let us know and we may interview you! Dr. Brianne Barker Stephanie N. Langel Vincent Racaniello

#ASV2024 official conference hotels are completely sold out, but there are still lots of hotel options (some are newly listed on ASV website) and OSU dorms remain available. Looks like the Columbus ASV meeting is gonna be one of the biggest and best ever! asv.org/asv2024/

So, *preliminary* molecular clock analyses indicate that the time of the most recent common ancestor (TMRCA) of the US cattle flu clade was late December.

TMRCA of that clade and the closest relatives in birds, mid-December.

If single intro, likely between those rough dates.

OK, I think we're close to decisive evidence that US bovine H5N1 had a single origin from birds, and that when related viruses from birds *have* been found, they are jumps from cattle back into birds.

Grackles, blackbirds, chickens all show mammalian adaptation like PB2 M631L.

any illusions that an approach that would detect these kinds of outbreaks much earlier and respond faster would be prohibitively expensive are dispelled by the certainty of future outbreaks that will have billion- or trillion-dollar price tags and cause unacceptable suffering.

It is so important to public health nationally & globally that Dept. of Agriculture release sequences & all associated meta data from the recent #H5N1 outbreak in dairy cattle, cats, and potentially humans.

Rick Bright Dept. of Agriculture Dept. of Agriculture_APHIS GISAID Initiative Wastewater for FluA virus in Texas
Highlighted Red line is River Road in Amarillo,Texas Panhandle
March 17th and April 16th are the two Peaks which are significantly above the rest of 2023-2024 Texas Flu Season
(note an earlier peak in February 20th-26th was also in Amarillo)

(1/2) Dept. of Agriculture published 239 genetic sequences of the U.S. H5N1 clade 2.3.4.4b influenza virus from samples associated with the ongoing highly pathogenic avian influenza outbreak in poultry/wild birds...

What I'm not really able to cover yet is the North American cattle situation - not enough sequencing or epidemiological data has been shared to draw any strong conclusions - see this recent piece by Helen Branswell 🇨🇦 This is frustrating to say the least... twitter.com/statnews/statu…