#MECFS is a severe multi-system illness. There is currently no diagnostic test, but did you know that studies have shown abnormalities at a group level in the brain, the central and autonomous nervous system, the immune system, and the cellular energy production? #MEAwarenessHour

Fluge et al., pilot study on subcutaneous anti-CD38 antibody daratumumab in moderate to severe #MECFS. For six responders of ten patients, mean SF-36 PF increased from 32.2 to 78.3. Low NK-cell count was significantly associated with lack of response. frontiersin.org/journals/medic…

Beentjes et al., comparison of traits for people with #MECFS and controls in UK Biobank data. Hundreds of traits differed between cases and controls, but single traits couldn’t distinguish case from control. The results cannot be explained by inactivity. embopress.org/doi/full/10.10…

Some researchers perpetuate the belief that #MECFS is psychogenic in nature. Did you know that many leading Universities now pursue biomedical research on ME/CFS and that many researchers accept the biological nature of the illness after reviewing the evidence? #MEAwarenessHour

The biopsychosocial approach for #MECFS was first introduced in 1988. The best evidence that this paradigm doesn’t work is the so-called evidence they present for it. No single properly conducted RCT for 37 years, but anecdotal evidence, correlations, strongly biased trials etc.

Good point! The bar for accepting bad science is much lower for biopsychosocial interventions than for pharmaceutical interventions. If a pharmaceutical company would use an RCT of the same quality as PACE to sell their stuff, there would be an outcry! x.com/sfadigacronica…

#MECFS is a severely debilitating illness that leaves about 25% of the patients housebound. Did you know that the illness does not only affect the lives of the patients, but that the quality of life of partners and other family members also is severely impaired? #MEAwarenessHour

#MECFS is a severe, neurological illness that affects tens of millions of people worldwide. People who want recognition. People who are waiting for help. People who want more and better research to be funded. Most of all: People who want their lives back! #MEAwarenessHour

Vink and Vink-Niese: “CBT and graded exercise therapy studies have proven that ME/CFS and long COVID are physical diseases, yet no one is aware of that.” frontiersin.org/journals/human…

The issue is not whether something is psychological or physical, but whether proposed interventions work. People with #MECFS have said, we don’t accept bad science such as biased trials or anecdotal evidence. We want evidence-based treatments that work! x.com/KH118118/statu…

#MECFS is chronic, complex multi-system illness that often leads to severe disability. Some doctors don’t take it seriously and argue that it is socially transmitted. Did you know that many doctors who developed long covid have changed their minds about ME/CFS? #MEAwarenessHour

Hilda Bastian comments on Cochrane’s exit from updating the review on exercise for #MECFS: “Not retiring influential out-of-date reviews is a ticking time bomb.” absolutelymaybe.plos.org/2025/07/31/six…

Post-exertional malaise in #MECFS is much more than fatigability! A paper from 2020 explains: “[PEM is] all-encompassing with symptoms affecting every part of the body, difficult to predict or manage, and requiring complete bedrest to fully or partially recover.” #MEAwarenessHour

New results from Dr. Jarred Younger: The #MECFS brain is inflamed! youtube.com/watch?v=wuzmYJ…

Did you know that radiological brain scans of patients with #MECFS have shown increased temperature, increased levels of lactate, microglia/astrocyte activation, and functional and structural abnormalities? This suggests an underlying pathology in the brain. #MEAwarenessHour