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New preprint online from the Stahelin lab and collaboration with the laboratory of Gregory Voth Voth Group lead by Mandira Dutta. Anionic lipid interactions of the SARS-CoV-2 nucleoprotein! biorxiv.org/content/10.110…

We had a wonderful week at Madeira! Thank you all for the great discussions at the FEBS Special Meeting on Sphingolipid Biology. It was a pleasure to host you all! #sphingolipidbiology #SLBiol2023 #visitmadeira FEBS EMBO Events Coskun Lipid Cellar @ ZML Dresden Bassereau Team Stahelin Lab

It’s Dr. Emily David, Ph.D.! This degree was made possible by the incredible support from my family and friends, my mentor, Stahelin Lab and lab mates, Purdue Borch MCMP dept., the Purdue Pharmacy, and PurdueMBTP program. Boiler up! Purdue University Photo by Chloe Smetanka

Excited to have this work published in the Journal of Lipid Research! How PI(4,5)P2 binding sites in the Ebola virus matrix protein modulate assembly and budding! KAJ the rockstar! Kristen A Johnson Journal of Lipid Research ASBMB Lipid Research Division (LRD) #lipidtime jlr.org/article/S0022-…

We are happy to have a new preprint online! Minor changes in electrostatics robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles biorxiv.org/content/10.110…

New work from the lab with integrated collaborative studies with Prem Chapagain's lab on the role of phosphatidic acid in assembly and budding of the Ebola virus. ASBMB Lipid Research Division (LRD) #lipidtime #ebola #VP40 sciencedirect.com/science/articl…

New work from our collaboration with the lab of Dr. Elsje Pienaar at Purdue. A computational model of the Ebola virus matrix protein nucleation-elongation process! #ebola #lipidtime journals.asm.org/doi/10.1128/sp…

Happy this manuscript is published, especially for Ph.D. student Bali Motsa. Demonstrates how +1 or -1 in charge (and more) can alter lipid binding, assembly, and budding of the Ebola virus matrix protein VP40. jbc.org/article/S0021-… #ebola #lipidtime #electrostatics #VP40

Learn more about how the Ebola virus matrix protein (VP40) dimer is stabilized! A wonderful collaboration with the Wiest and Chapagain labs integrating computational work with in vitro and cellular studies. #ebola #vp40 #lipidtime #Virus onlinelibrary.wiley.com/doi/full/10.10…

Abstracts Due 5/26!🌟 Explore the latest in #Phospholipid Biology at #LSHSRC! Join Antonella De Matteis Tigem Telethon and Haucke lab in July for "Phospholipids in Aging and Disease." Topics: lipid signaling, treatments for diabetes, cancer, & more. bit.ly/3xQj5yp

Collaboration with Dr. V. Jo Davisson's lab! New studies demonstrating potency and stability of diphyllin-derived Vacuolar-ATPase inhibitors #Virus #pH sciencedirect.com/science/articl…

Collaboration with Dr. Elsje Pienaar's computational lab yields a better understanding of the Ebola virus nucleoprotein's role in virus budding. #Ebola #nucleoprotein #VP40 nature.com/articles/s4200…

The N (nucleoprotein) interacts with anionic lipids including phosphoinositides and phosphatidylserine. New work from the lab and collaboration with the lab of Greg Voth. #lipidtime #sars2 #membrane jbc.org/article/S0021-…

New collaborative work examining electrostatic interactions between the Ebola virus matrix protein VP40 and the plasma membrane at key arginine substitutions! pubs.acs.org/doi/10.1021/ac… #ebola #lipidtime #VP40 #membrane #filovirus

Fatty acids and membrane order matter for assembly and budding of the Ebola virus matrix protein VP40! New work from the lab. Big thanks to Andrea Marzi! #ebola #lipidtime #membrane #VP40 #plasma_membrane jlr.org/article/S0022-…

Very pleased to announce a new review in Virology put together by Ph.D. student Rokaia Sultana. This article details the strenghts and limitations of virus-like particle systems for SARS-CoV-2 #virus #sarscov2 #lipid #virology sciencedirect.com/science/articl…

Check out our new preprint! biorxiv.org/content/10.110… We found sphingolipid binding to SARS-CoV-2 M protein controls its conformation to coordinate viral assembly+release. Great collaboration with Voth Group + Stahelin Lab co-led by @KimDolan_UCB, Mandira Dutta, + Souad Amiar.

Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly New preprint in collaboration with the Steve Brohawn Voth Group Excellent team effort demonstrating a ceramide-1-phosphate interaction in M! #membrane biorxiv.org/content/10.110…

I was very happy our work was chosen to the cover this month. Especially for former postdoc Souad Amiar and collaborator Andrea Marzi Cover - Journal of Lipid Research jlr.org/article/S0022-…

New publication! It was a wonderful collaboration with the lab of Juan Del Valle at Notre Dame. This would not be possible without his team and their peptide design. A constrained peptide that binds the Ebola virus matrix protein #ebola #VP40 #peptide pubs.rsc.org/en/Content/Art…