acrjournals.onlinelibrary.wiley.com/doi/10.1002/ac… New pub just came out. We found the paradoxical relation of opioid use and pain increase is mediated by pain sensitization but modestly. Other factors, such as psychological symptoms, may play an important role in opioid-induced hyperalgesia??

#ACR23 #countdown Sun Nov 12 Poster – Epi Abstract # 0147 S. Reza Jafarzadeh Matthew Baker M.D., M.S. BU/BMC Rheumatology Stanford Rheumatology acrabstracts.org/abstract/leuko…

Louise Thoma Ashima Makol MD Alicia Hinze, MD, MHS #0147 S. Reza Jafarzadeh Matthew Baker M.D., M.S. BU/BMC Rheumatology Stanford Rheumatology OA drug repurposing study using observational data Research Q: Can leukotriene inhibitors (montelukast, zafirlukast, or zileuton) prevent PTOA in people who have undergone ACL or meniscal surgery following injury? #ACR23

Congratulations to my BU/BMC Rheumatology colleagues on your Rheumatology Research Foundation awards!

"It's called 'REsearch', not 'search', because most of the time you don't get it perfect on the first try." The kind words of Reza Jafarzadeh S. Reza Jafarzadeh on my research challenges. Get colleagues like this, folks!

NEW PREPRINT Using the estimands framework for prediction models with updated predictions over time arxiv.org/abs/2311.17547

Congratulations to Dr. Corrigan for being awarded a $375k research grant! #DCHSlife #SLUPT

I’m excited to start this project and learn about pain and motor learning from my mentors! Thank you Rheumatology Research Foundation for the continued support! @lfreylaw S. Reza Jafarzadeh and #TwitterlessOthers

Erik van Zwet guido imbens Steven Goodman NEJM Evidence Andrew has posted a blog page for the paper at statmodeling.stat.columbia.edu/2023/12/23/bay… which among its cites are our 2008 and 2014 debates on informative Bayes statmodeling.stat.columbia.edu/2008/02/05/spe… and Bayesian vs frequentist diagnostics statmodeling.stat.columbia.edu/2014/08/11/dis… to show how our thinking has evolved.

Registration is OPEN for the 2024 American Causal Inference Conference (ACIC). #researchopportunity 📍 Location: Seattle, WA 📅 Dates: May 14 – 17, 2024 Abstract Submission Deadline: 1/11/24 Learn more: sci-info.org/annual-meeting/ #publichealth #causalab

Rheum Research in Brief Mediating Effect of Pain Sensitization on the Paradoxical Relation of Taking Opioids to Pain Severity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study In AC&R loom.ly/0mfxXv8

🎙️ Season 5 Episode 2 (our 50th episode!) is live! Dr Ellie Murray, ScD & Lucy D’Agostino McGowan chat with Mark van der Laan (Mark van der Laan) about Targeted Learning — let us know what you think!

Recognition of BU/BMC Rheumatology faculty David Felson & Tuhina Neogi, MD, PhD receiving The National Institute on Aging (NIA) grant to study #osteoarthritis: What Causes Osteoarthritis? BU Researchers Win $46 Million Grant to Pursue Answers and Find New Treatments bu.edu/articles/2024/…

Richard Starmans (Utrecht University and Tilburg University, the Netherlands) and I  wrote our "pilot" for a future series of philosophical statistical dialogue style articles, entitled "LASSO and beyond...Highly Adaptive  LASSO". github.com/markvanderlaan…

Longitudinal Targeted Minimum Loss-based Estimation with Temporal-Difference Heterogeneous Transformer ift.tt/1o7XqYI

A crossover* in the story of GLP1 agonists vs SGLT2 inhibitors: drug repurposing for knee OA S. Reza Jafarzadeh #OARSI2024 BU/BMC Rheumatology *like a movie crossover, not the study design!

Thank you to the Arthritis Foundation for their generous grant to support our research BU/BMC Rheumatology

What are the differences between one-step estimation, Double ML, and Targeted ML? This commentary (Iván Díaz) and blog post (Mark van der Laan) provide an overview of the history of machine learning in semiparametrics. pubmed.ncbi.nlm.nih.gov/31742333/ vanderlaan-lab.org/2019/12/24/cv-…

When is #causal interpretation appropriate in observational studies? CAUSALab faculty member Issa Dahabreh & Kirsten Bibbins-Domingo propose a new framework for medical journal causal communication in @JAMA. Read the full article: jamanetwork.com/journals/jama/… #hsph #harvardchan #causalab

With #TargetTrial emulation becoming increasingly popular, it's important to understand what it can and cannot do. In this new podcast, I discuss how target trial emulation can 1) improve causal inference from observational data, and 2) extend inferences from randomized trials.