Soos OrgCat Lab
@soosgroup
Synthetic organic chemistry group focused on organocatalysis, frustrated Lewis pairs, strained heterocycles and natural product total synthesis. (Student-run)
ID: 1265940078548975623
https://www.orgcat.hu 28-05-2020 09:37:03
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Congratulations to Brandon Wright , Alessio Regni ,and Nattawadee Chaisan on the beautiful synthesis of daphenylline in JACS. pubs.acs.org/doi/epdf/10.10…
It’s out! Check our nature publication about charge relocation! nature.com/articles/s4158… Congratulations to the team! #Bogdan Giulia Iannelli Daniel Kaiser #oxacarbeniumgang
A few years ago, we uncovered an unusual Z-selective allylic functionalization. We had no idea whatsoever how it worked. Karina and Achyut Ranjan Gogoi teamed up to map out the full mechanism and identify the origin of stereoinduction!! Check out our first detailed mechanism paper!
Building upon the inspiration from yesterday's talk during his visit to Budapest, today's highlight was the chance to connect with Ben Feringa from Feringa Lab and delve into intriguing scientific discussions with fellow group members. His insights are deeply appreciated!
Happy to share our work on bioinspired meroterpenoids synthesized in the The Magauer Lab that induce a lipid mediator class switch to inflammation resolution, available now as preprint: biorxiv.org/cgi/content/sh… #inflammation #oxylipin #lipidomics #lipoxygenase #proresolving
Direct olefin difunctionalization using anomeric amides, without catalysts & additives! The products, MultiFunctional HydroxylAmines (MFHAs), are building blocks for the synthesis of complex amines. Kudos to Young-Do Young Do Kwon & Daniel Daniel Joaquin! chemrxiv.org/engage/chemrxi…
Here we introduce the concept of a "structural pin," a hydrogen bond that predominantly dictates the conformation of a macrocycle. This discovery offers a tool for examining the dynamic behavior of macrocycles and optimizing their structures. Angewandte Chemie onlinelibrary.wiley.com/doi/10.1002/an…
A tribute to Katritzky chemistry: we're excited to share how benzotriazole aids in amide bioisostere construction onlinelibrary.wiley.com/doi/10.1002/an… Mykhailiuk Chem 🇺🇦 Angewandte Chemie
We are happy to share our joint paper with Prof. Tibor Soós (Soos OrgCat Lab): "Strain-Release-Driven Modular Synthesis of Oxetane-Based Amide Bioisosteres: Concise, Robust and Scalable Approach," co-authored by Enamine scientists: Yarema Galushchak and Pavel Mykhailiuk
Excited to share our newest strategy to access carbenes from aldehydes - now via radicals! Young & Jake found this highly practical, efficient, & selective way to make triangles - that even works in the presence of air or water! J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…