Structure–Activity Relationships and Target Selectivity of Phenylsulfonylamino-Benzanilide Inhibitors Based on S1647 at the SLC10 Carriers ASBT, NTCP, and SOAT pubs.acs.org/doi/full/10.10…

Mitochondrial pyruvate carriers control airway basal progenitor cell function through glycolytic-epigenetic reprogramming cell.com/cell-stem-cell…

The deubiquitinase OTUD5 stabilizes SLC7A11 to promote progression and reduce paclitaxel sensitivity in triple-negative breast cancer sciencedirect.com/science/articl…

Exploring fructose metabolism as a potential therapeutic approach for pancreatic cancer nature.com/articles/s4141…

Evolution, classification, and mechanisms of transport, activity regulation, and substrate specificity of ZIP metal transporters tandfonline.com/doi/abs/10.108…

Genetically encoded green fluorescent sensor for probing sulfate transport activity of solute carrier family 26 member a2 (Slc26a2) protein nature.com/articles/s4200…

Fluorescent non-canonical amino acid provides insight into the human serotonin transporter nature.com/articles/s4146…

Facilitation of Mg2+ Extrusion by the Murine Distal Convoluted Tubule-Specific Isoform of SLC41A3 journals.lww.com/jasn/citation/…

The zinc transporter Slc30a1 (ZnT1) in macrophages plays a protective role against attenuated Salmonella doi.org/10.7554/eLife.…

Membrane potential stimulates ADP import and ATP export by the mitochondrial ADP/ATP carrier due to its positively charged binding site | Science Advances science.org/doi/10.1126/sc… Congrats Edmund Transporters and Solute carriers lab!

Hepatocyte-specific SLC27A4 deletion ameliorates nonalcoholic fatty liver disease in mice via suppression of phosphatidylcholine-mediated PXR activation sciencedirect.com/science/articl…

Unraveling the socio-cognitive consequences of KCC2 disruption in zebrafish: implications for neurodevelopmental disorders and therapeutic interventions frontiersin.org/journals/molec…

Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistancel cell.com/cancer-cell/fu…

SLC13A3 story 1 (the beneficial one ✅): SLC13A3 was recently discovered to be an itaconate importer that improves hepatic antibacterial innate immunity cell.com/developmental-… Developmental Cell

We found a #VHH antibody that allosterically inhibits sialic acid binding by the #TRAP transporter #SBP VcSiaP. Thanks to the team Philipp Hendricks Martin Peter Sophie Binder Matthias Boehnke @SMenzel @ Gavin H Thomas @GHagelueken Read the full story here: doi.org/10.1038/s42003…

Membrane transporters modulating the toxicity of arsenic, cadmium, and mercury in human cells life-science-alliance.org/content/8/2/e2…

ATP-Binding Cassette and Solute Carrier Transporters: Understanding Their Mechanisms and Drug Modulation Through Structural and Modeling Approaches mdpi.com/3062618 #mdpipharmaceuticals

1/4 I am happy to share my new publication in PNAS entitled “Structural basis of disease mutation and substrate recognition by the human SLC2A9 transporter” (pnas.org/doi/abs/10.107…).

Lactate signalling leads to aggregation of immune-inflammatory hotspots and SLC5A12 blockade promotes their resolution go.nature.com/4miXXoV

Cellular pan-chain acyl-CoA profiling reveals SLC25A42/SLC25A16 in mitochondrial CoA import and metabolism go.nature.com/4pktc4M