Frozen in stone for 310 million years, scientists found an exceptional imprint of a horseshoe crab's brain along with other bits of the creature’s nervous system nyti.ms/37ZSJcO

Human Cell Atlas #cellxgene is a tool that makes it easier for researchers without computational training to share, explore + analyze single-cell biology datasets It's the largest collection of open single-cell data to date, with ~17.5M cells across all major organs cellxgene.cziscience.com/?utm_campaign=…

Happy Halloween from the Walsh lab! 🎃

Double rainbow sighting on Halloween! -- a sign that my experiment will work or that I need to buy a bag of SKITTLES on my way home? 🤔

WE'RE HIRING A NEW TEACHING PROFESSOR IN NEUROBIOLOGY! 🧠🚨 Join UCSD BioSciences in developing our undergraduate neurobiology curricula & in advancing the research on teaching & learning at UC San Diego! Apply at this link, details in thread.👇 apol-recruit.ucsd.edu/JPF02972

Some good news to start the month: a new paper from us Harwell Lab is out today in eLife - the journal! This is our first deep dive into the septum - you can find it here: elifesciences.org/articles/71545, and/or read a small thread below describing what we did (1/10)

Our latest paper is out eLife - the journal! We take a look at the septum, trying to understand how its neuronal diversity is specified during development. Miguel Turrero García summarizes the story here:

I wanted to see snow one last time before I leave Boston and I got my wish! ❄️

Excited to share our story on the role of RA signaling on cone survival during retinal degeneration! It's been known for decades that cones in the peripheral retina survive longer in rod-cone degeneration mice, but it was unclear why. Here's our attempt: biorxiv.org/content/10.110…

Snowy visit to Harvard University yard. ❄️ Bye for now, John! Hope to see you again in the future.

A student who is coming to interview in one of our graduate programs asked me for advice about interviews. So, here is my guidance, in case it's useful. Hopefully others will add their own.

🎄!

Already I feel that 2022 is going to be a much better year.

The adult zebrafish brain atlas (AZBA) is a new tool for the 3D exploration of adult zebrafish brains. elifesciences.org/articles/69988…

Excited to share our new paper in Orli Bahcall! Can a mutation really hit the same place twice? We found biallelic mutations across 2,658 cancer genomes that contradict the famous infinite sites assumption and highlight the processes behind them: nature.com/articles/s4158…

Turns out development of human cerebral cortex is unlike any animal ever described! Latest work from Sonia Nan Kim (Sonia N. Kim) and twitterless Vinay Viswanadham Peter J Park lab, using clonal mutations and cell types sampled across human cortex. biorxiv.org/content/10.110… A thread.

Excited to share our preprint -- cell lineage analysis using somatic mutations to learn about neuronal cell types and arealization in the human cortex!🧠🧬