Michelle Smyth (@smythm86) 's Twitter Profile
Michelle Smyth

@smythm86

Clinical Research Nurse @RCSICritCare

PI @Irish_RNM
Critical Care Nurse
All remarks my own

ID: 854957995083649024

calendar_today20-04-2017 07:20:45

366 Tweet

214 Followers

372 Following

Michelle Smyth (@smythm86) 's Twitter Profile Photo

First trial presented as part of #CCR25 #TARGETPROTEIN No difference in number of days free of the index hospital and alive at day 90

Michelle Smyth (@smythm86) 's Twitter Profile Photo

#ENCOMPASS trial being presented as part of #CCR25. Electronic healthcare record allowing patients to be identified for inclusion in the study

#ENCOMPASS trial being presented as part of #CCR25. Electronic healthcare record allowing patients to be identified for inclusion in the study
Michelle Smyth (@smythm86) 's Twitter Profile Photo

#UKROX patients recruited within ~5hrs of ventilation. Would love to see the breakdown of who randomised patients and tools etc used. Fantastic effort in recruitment of patients. Study completed with 3 years and started tail end of COVID19

#UKROX patients recruited within ~5hrs of ventilation. Would love to see the breakdown of who randomised patients and tools etc used. Fantastic effort in recruitment of patients. Study completed with 3 years and started tail end of COVID19
Michelle Smyth (@smythm86) 's Twitter Profile Photo

#NOTACS embedding patients into all elements of the trial from design of trial to publication of results. Wonderful to see #CCR25

#NOTACS embedding patients into all elements of the trial from design of trial to publication of results. Wonderful to see
#CCR25
Michelle Smyth (@smythm86) 's Twitter Profile Photo

Excellent editorial of the #NOTACS trial by Dr. Niall Ferguson Need to find the sweet spot for balancing outcomes - patient, clinical and intervention #CCR25

Excellent editorial of the #NOTACS trial by <a href="/nialldferguson/">Dr. Niall Ferguson</a>

Need to find the sweet spot for balancing outcomes - patient, clinical and intervention 
#CCR25
Michelle Smyth (@smythm86) 's Twitter Profile Photo

How do you do a trial that recruits ~43000 patients...team work, communication and a multi-centre, randomised cluster cross-over trial using only 7 site! Data collected using the provincial health database. #CCR25 #FLUID #FLUIDtrial

How do you do a trial that recruits ~43000 patients...team work, communication and a multi-centre,  randomised cluster cross-over trial using only 7 site!
Data collected using the provincial health database. 
#CCR25 #FLUID #FLUIDtrial
Michelle Smyth (@smythm86) 's Twitter Profile Photo

Final day of #CCR25 and starting with ##GASTROSAM Fantastic achievement to see this important study completed in challenging environments - covid 19, military coup, flooding. In awe of the research and clinical teams for completing this study 👏

RCSI (@rcsi_irl) 's Twitter Profile Photo

How does Alpha-1 antitrypsin therapy reduce inflammation? Researchers RCSI Anaesthesia and Critical Care show it blocks a key immune signalling pathway, increasing our understanding of inflammation in people with Alpha-1 antitrypsin deficiency (AATD). ➡️ doi.org/10.1136/thorax… #RCSIdiscover

How does Alpha-1 antitrypsin therapy reduce inflammation?

Researchers <a href="/RCSICritCare/">RCSI Anaesthesia and Critical Care</a> show it blocks a key immune signalling pathway, increasing our understanding of inflammation in people with Alpha-1 antitrypsin deficiency (AATD).

➡️ doi.org/10.1136/thorax…

#RCSIdiscover
Marion Campbell (@marionkcampbell) 's Twitter Profile Photo

At #CCR25, we saw some trials use a #CompositeOutcome (an endpoint that combines more than one outcome into a single measure) & also saw some of the problems these can throw up. I have discussed these before but thought it would be useful to revisit 1/9 #MethodologyMonday #120

Marion Campbell (@marionkcampbell) 's Twitter Profile Photo

Over recent weeks I’ve heard about some trials struggling with the phenomenon known as “Lasagne’s Law.” I’ve flagged this issue before, but always good to revisit it and discuss what can be done to minimise it 1/7 #MethodologyMonday #121

Michelle Smyth (@smythm86) 's Twitter Profile Photo

First time attending UKCRF Network conference. Fantastic two days in Birmingham with excellent speakers and informative parallel sessions. Coming away with even more knowledge and tools in the tool kit 🔧 looking forward to 2026 in Dublin 🇮🇪 #UKCRF #CRFBRC25

First time attending <a href="/NIHR_UKCRFN/">UKCRF Network</a> conference. Fantastic two days in Birmingham with excellent speakers and informative parallel sessions. Coming away with even more knowledge and tools in the tool kit 🔧 looking forward to 2026 in Dublin 🇮🇪
#UKCRF #CRFBRC25