Almost certainly increases have to do with improved diagnostic imaging and CSF biomarkers. Ignore the nonsense that will no doubt manifest in replies to this tweet. Prion doctors are continually on the lookout for alternative exposures leave that to us to worry about.

Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults. Fascinating study I look forward to replication evidence. Seems as though statins convert APOE4 risk of AD to reference genotypes risk. neurology.org/doi/10.1212/WN…

The Observer view: children catastrophically failed by the medical profession. not really all Drs looking away, as a generality we don’t comment on fields we don’t have expertise in. Suggest down to commissioners/ Trust leaders/ Royal Colleges oversight theguardian.com/commentisfree/…

There is no ‘backstory’ to ending of 2/care NHS Practitioner Health other than (we’re told) - no budget. To remind, it was established following suicide of a psychiatry who also killed her baby and highlighted the barriers doctors have in accessing mental health care.

The Cass review: an opportunity to unite behind evidence informed care in gender medicine | The BMJ bmj.com/content/385/bm…

Thing about Ripley isn’t it crazy that Inspector Ravini hasn’t asked to look at a photo of Dickie or Tom. He seems quite diligent. This would immediately reveal what’s going on.

uclh.nhs.uk/work-with-us/c…
We are recruiting a new clinical fellow in neurology (or psychiatry) at ST1-5. You will gain experience in all human prion diseases, become an expert in multidisciplinary management of rapidly progressive dementia and be exposed to world-class research.

*Update* — we are now hiring for a study coordinator AND a biomarker research assistant to work on the UCL blood biomarker challenge ADAPT study. Please apply/spread the word. ucl.ac.uk/work-at-ucl/se… ucl.ac.uk/work-at-ucl/se…

I am surprised at how painful my ankle injury has been, and not sleeping, but today i had a lie-in it feels quite a bit better and I’m at my desk looking forward to working. The garden on the other hand is a jungle.

Probably should add yeast prions to the list of hypotheses of environmental sources science.org/doi/full/10.11…

Congrats to Gustavo Pradilla and team Emory Neurosurgery on ENRICH trial now out in NEJM. Minimally invasive surgical hemorrhage evacuation lowers mortality/improves outcome for lobar ICH. nejm.org/doi/full/10.10…

Some sense long overdue 👏

What a morally bankrupt organisation Amnesty International has become. They eulogise the memory of a man who kidnapped 19-year-old Moshe Tamam and held him hostage for 2 days, then gouged out his eyes, castrated him, mutilated his body, and finally shot him in the chest and dumped his body.…

🧵 (1/6) Two years ago, when I only started digging into the current state of aging research, I was much more optimistic about our progress. I read articles like Laura Deming's Longevity FAQ, which lists '95 things that make mice live longer', and thought: 'Well, at least we have…

Super clear well written paper I imagine many of these problems persist in observational studies

The Killing of a Sacred Deer watched tonight. Super movie Dir Yorgos Lanthimos, Barry Keoghan excellent. Maybe everyone has seen this it’s nearly 7 years old now but I missed it first time around.