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As 2024 starts, I’d like to reflect on some of the fantastic papers that nature published in human and cognitive neuroscience, ranging from fundamental discoveries, such as the somato-cognitive action network, using neuropixels in humans and a multimodal speech neuroprosthesis🧵

The brainstem’s red nucleus was evolutionarily upgraded to support goal-directed action (biorxiv.org/content/10.110…) ... Originally for quadrupedal locomotion, it is for action in humans. Functionally connected to the action (CON, SCAN) and salience networks, including ant.

How to find massive motor plasticity effects in the subcortex? Find out in our preprint. biorxiv.org/content/10.110… Turns out these new findings change our understanding of #Parkinson disease and some #sleep processes. Let me unfold it With Nico Dosenbach @gordonneuro Dillan Newbold

Now at JAMA Pediatrics We used two large independent surveys of high school students (N> 15K each) to examine dose-response associations between substance use (alcohol, cannabis, and nicotine) and suicidal thoughts and other psychiatric comorbidities. jamanetwork.com/journals/jamap…

Introducing the Action-Mode Network – AMN. Better late than never! 17 years ago, we clumsily called this the Cingulo-opercular Network (CON) based on its anatomy (we weren’t exactly sure what it does). Now we’ve finally got the evidence to give it the functional name it deserves:

1/3 Backlog in announcing preprints, but here's goes! Preprint #1 by Pansheng Chen doi.org/10.1101/2023.1… We previously proposed a meta-matching framework to translate predictive models from a single large dataset to predict new phenotypes in small data. Here we extend the ...

Super excited about this new preprint. Will do a thread on it later today.

An incredible amount of work (134 page supplement!) for a fundamental question of how to best employ MRI for brain based predictions. When in doubt, get more data. Another instant Thomas Yeo lab classic…

We found an issue with a specific type of brain imaging study and tried to share it with the field. Then the backlash began. By Nico Dosenbach and Scott Marek thetransmitter.org/fmri/breaking-…

Breaking down the winner’s curse: Lessons from brain-wide association studies thetransmitter.org/fmri/breaking-…

Our paper “A Precision Functional Atlas of Personalized Network Topography and Probabilities” is out now in Nature Neuroscience! The MIDB Precision Brain Atlas is a collection of individualized neural network maps from n~10,000 and probabilistic atlases (1/8) rdcu.be/dCvuC

Ever wonder how people's brains differ from one another? ➡️ Individual differences in 🧠 organization commonly come in 2 forms: shifts in borders & 'ectopic intrusions' far from expected locations Now out in Nature Neuroscience, led by Ally Dworetsky rdcu.be/dGeIp 🧵soon!

(1/13) We are beyond delighted to announce the public release of the data for the Reproducible Brain Charts (#RBC) effort – a 100% open data resource for study of the developing brain + psychiatry, funded by National Institute of Mental Health (NIMH) reprobrainchart.github.io

My lab, part of MIDB, is a hiring a senior coordinator/lab manager! Ideal candidate will have experience managing research and an interest in precision brain imaging + clinical trial research. R/t share! D/m, email with questions. Job id: 362340 hr.myu.umn.edu/psc/hrprd/EMPL…

After a high dose of psilocybin, the brain desynchronizes at a massive scale, causing loss of our sense of self, time, and space. This may drive the burst of plasticity caused by psychedelics. The next day, brain activity has largely returned to normal, but an echo remains – a

Now available open-access online Neuropsychopharmacology ! Our review "Psychiatric neuroimaging designs for individualised, cohort, and population studies" nature.com/articles/s4138…

Happy to share that our work applying precision mapping to individuals with depression sampled longitudinally over an extended period has been published this week in @nature. Brief recap of the main findings and their potential implications below. nature.com/articles/s4158…

In the action-mode, arousal is heightened, attention focused externally, and plans are converted to goal-directed movements and updated based on feedback, such as pain. The brain’s action-mode is created by a dedicated action-mode network (AMN) rdcu.be/d5odm. In the

But it's ok for Elon and his bros to dive into ... since they know NIH mechanics? ..... 🤔🤔🤔

Indirects helped keep the lights on and your toilet flushing while you were being educated at Penn. You were a failure without government help technocrat