We're thrilled to announce that the U.S. FDA has granted Fast Track designation for VERVE-102 for the treatment of patient groups with hyperlipidemia and high lifetime #cardiovascular risk to reduce low-density lipoprotein cholesterol (LDL-C). VERVE-102 is a novel, in vivo,

“For gradient descent to get stuck in a local minima, it would have to get stuck in every dimension at once”. This is very counterintuitive to humans, we think of local minima as common phenomena. Local minima become less and less common as the number of free variables goes up.

NotebookLM is one of the few AI products that feels like magic It took them 1.5 years, but today they finally launched a mobile app Google has the best AI tech. We'll see if that's enough to overcome their awful go-to-market execution. Historically, it has been

The computer scientist Ryan Williams recently devised a mathematical procedure for transforming any algorithm — no matter what it does — into a form that uses much less computing space. “I just thought I was losing my mind.” quantamagazine.org/for-algorithms…

wow ~24,000 NEW PRs overnight from Codex after OpenAI expands access to free users. sheeeeesh

Holodeck before 2030

Breaking the sound barrier, again. Today, Donald J. Trump issued an executive order that effectively lifts the 52-year ban on civil supersonic flight over land in the U.S. It directs the FAA to repeal the supersonic speed limit as long as aircraft don’t produce an audible sonic

A federal judge has ruled that Anthropic's use of books to train Claude falls under fair use, and is legal under U.S. copyright law.

We must stop AI before it saves more lives! 🤖

attentionmech Assuming the stuff going through our corpus is a decent analogy for the “residual stream”... There are approx 200mil axonal fibers in the corpus collosum (of which 1-5% are active). A neuron can send around 100 bits/sec. So that gives 0.2-1Gbps of bandwidth for the widest

Whoah! The Peripheral is not going to be sci-fi for long. Imagine being able to receive a video/audio stream from the bot while controlling it remotely. Can’t wait to see Blindsight in action. Elon Musk and team are making incredible progress!

Andriy Burkov I find QCA (quantum cellular automata) and other discrete computational models easiest to understand intuitively because they show where the abstractions lie. Think of a lattice where each node holds a state vector. Each vector represents the state of each field at that point in

Extremely promising gene therapies in the pipeline for those with high genetic heart disease risk! Turning off PCSK9 leads to “lifelong benefits with no known downside”. This should be a strongly recommended option during IVF or even after birth. Totally unnecessary suffering for

Luís Dias Gary Marcus Progress doesn’t just halt when there’s unlimited economic incentive for it to keep going. For example, we’ve hit “the end of moore’s law” every year for the last two decades. Guess what? That curve continues to be as exponential as ever, even though the number of new

Luís Dias Gary Marcus Incentive may have been the wrong word, more like “economic momentum”. It’s hard to stop it once it’s at full force focused on a singular goal. “Alchemy” never built momentum for obvious reasons, but it did turn into chemistry, which eventually built enormous economic momentum.

This is a common fallacy. The derivation or reasoning process itself can be “in-distribution” and still lead new (unexplored) out of distribution results. AI can write new proofs and discover new mathematics/physics for the same reason it can write new functional code. The

You’re welcome!

'water is transparent only within a very narrow band of the electromagnetic spectrum, so living organisms evolved sensitivity to that band, and that's what we now call "visible light". ' (found via HN)

The FDA queue is full of one and done in-vivo CRISPR gene editing therapies for many incurable chronic diseases. The future is going to be wild!