𝗠𝗲𝗲𝘁 𝗠𝗲𝘁𝗔𝗚𝗘! 🎉 Researchers from Graz and Vienna team up to tackle ageing at the metabolic level — and shape a healthier future. Details 👉 metage.at #HealthyAging #Metabolism #ScienceCommunity #AcademicLife #ResearchNetwork

Nicotinamide modulates gut microbial metabolic potential and accelerates recovery in mild-to-moderate COVID-19 go.nature.com/4dkeG7A

The best part of ISHR2025 in Nara world congress countless catch ups, coffees, dinners and cocktails with 🌍scientific family 🫀🫶🏻 Dr Kate Weeks Anja Karlstaedt Simon Sedej Luc Bertrand Prof Rebecca Ritchie Heather Group Kim Mellor Lea Durham Delbridge Bell-Lab: Cardiac Disease Mechanisms John R. Ussher Davor Pavlovic

Our work has been selected for the May @circres Podcast! Listen the interview with Francesco Paneni and #SarahCostantino about the role of chromatin remodeling in #HFpEF Marialucia Telesca Shafeeq mohammed Era Gorica Natalia Atzemian Ludovica Di Venanzio Alessia Mongelli Nazha Hamdani

Pleased to share our latest paper Inhibition of Adipose Tissue Lipolysis Treats Obesity-Related HFpEF Mahmoud Abdellatif Med Uni Graz Circulation Research ahajournals.org/doi/10.1161/CI…

👥 Meet the people behind MetAGE! Researchers from 4 institutions - from basic science to clinical application - are joining forces to understand how metabolism shapes healthy ageing. Together, we’re driving innovation in ageing research. 💡#HealthyAgeing metage.at

Zhakeer & colleagues found that the #NLRC3-#IL18 axis in Treg cells links immune dysregulation to #EndMT, providing mechanistic insights into #PH-LHD pathogenesis. Learn more at ahajrnls.org/45cyrf1

One of the first publications resulting from our Cluster of Excellence by Schweiger_lab and colleagues (including this beautiful cover image)! Check it out 👇 #MetAGE #healthyaging #longevity #microscopy #adiposetissue

⁩Thomas Rau from the Schweiger_lab presents an easy to use approach for whole-mount labeling and quantification of neuron- and vessel-density in adipose tissue in journal of cell science (JCS⁦⁦⁩), ⁦Uni Graz/University of Graz

Link to publication: journals.biologists.com/jcs/article/13…

Here's what our research cluster does: We study how aging affects metabolism and vice versa – and what we can do to increase our healthy life span. #HealthyAgeing #MetAGE #ScienceToAction #longevity #translationalresearch

Simon Kraler recieves the annual Award for the Best Dissertation of the Medical Faculty of the University of Zurich - congratulations! The Center for Molecular Cardiology is proud to know the best of the next generation aming its rembers. An impressive achievement for both.

CardioTomLuscher Simon Kraler, congratulations and very well deserved! We are also proud of you.

Circulation Research May 23rd Issue is Out! Compendium on Interorgan Crosstalk in Heart Failure and Cardiometabolic Diseases In this issue read 14 reviews & 5 Research Letters: ahajrnls.org/4kaMnLo Gabriele G. Schiattarella Maria Kontaridis

The compendium on interorgan crosstalk in HF is finally out. Glad we have contributed a research letter showing that inhibition of adipose tissue lipolysis treats obesity-related HFpEF. Circulation Research Mahmoud Abdellatif Prof. Dr. Andreas Zirlik Med Uni Graz COST Action EU-METAHEART ahajournals.org/doi/10.1161/CI…

Circulation Research Compendium on Interorgan Crosstalk in #HeartFailure and #Cardiometabolic Diseases @Instckner et al Research Letter "Inhibition of #Adipose Tissue #Lipolysis Treats #Obesity-Related #HFpEF" ahajrnls.org/43EBJFH Simon Sedej Prof. Dr. Andreas Zirlik @mah_abdellatif

Not the only, but one reason, why our research is so important 👇 #healthyaging #longevity #metage #metabolicflexibility

🫀New publication from our cluster researchers: Blocking fat breakdown - not just eating less - may better treat #obesity-related heart failure (#HFpEF). Fat tissue might hold the key.👇 Simon Sedej Mahmoud Abdellatif Prof. Dr. Andreas Zirlik Uni Graz/University of Graz Med Uni Graz TU Graz #MetAGE

🚨New from our group in Circulation Research We identify a FoxO1-zDHHC4-CD36 S-acylation axis driving metabolic + contractile dysfunction in the diabetic heart. Blocking this pathway reprograms FA metabolism and improves heart function. Read more: 🔗 ahajournals.org/doi/full/10.11…

Kaitlyn Dennis et al found #FoxO1-zDHHC4-#CD36 S-acylation axis drives metabolic dysfunction in #diabetes. Learn more at ahajrnls.org/3Zpvc0g @heatherlab.bsky.social Heather John R. Ussher Will Fuller Dunja Aksentijevic Ricciarelli Marcos Castro Guarda @ujangpurnama