Author response from Yotis Senis now added to this preLight, giving us a sneak peek into ongoing research: doi.org/10.1242/prelig…

I'm delighted to announce that the Earley Lab will be moving to URMC Department of Pharmacology & Physiology as of August 1! We have multiple positions for postdocs, res. scientists, and Ph.D. students interested in vascular TRP channels, blood flow in the brain, and cSVDs.

Biggest paper yet from the lab out now in Immunity! It is a massive #openscience resource on #tissueTregs, and what makes #Tregs tick in the #tissues. Spoiler-alert: Tissue Tregs are really different from what we all thought. 🧵 1/21 sciencedirect.com/science/articl…

Will complement inhibitors ever be useful for treating TRALI? What mediators should we target in antibody-mediated rejection? Some discussion of questions raised by our study in new issue of @JClinInvest: jci.org/134/12#letter_…

Paper of the week ECCO! We found evidence that IgG hexamer assembly (depicted in this animation from Genmab) drives lung injury responses that can be triggered by alloantibodies: jci.org/articles/view/…

Amazing! TLR activation leads to assembly of barrel-shaped MyD88 superstructures (myddosomes) that detach from TLRs to signal:

Fibroblasts are everywhere in our tissue as structural cells, yet we are only beginning to understand them. Today in nature, we report that lung-specialized alveolar fibroblasts orchestrate lung homeostasis, inflammation, and fibrosis. 🧵👇(1/n) nature.com/articles/s4158…

King's Prize Fellowship scheme open for early/mid-career researchers. Great opportunity for independent research and to get on the career ladder. Deadline 28 Nov. Internal and external applicants welcome. Details ⬇️ #Fellowship

⁦The University of Manchester⁩ has honestly been the most amazing place to start and then develop my lab over the last five years. I am so grateful to the community we have here and this is such a fantastic opportunity for the right candidate. Please get in touch! jobs.manchester.ac.uk/Job/JobDetail?…

Have a PhD and interested in a career in sci comm & working with preprints? Come work with us at bioRxiv/medRxiv! schooljobs.com/careers/cshl/j…

In our new paper out today nature.com/articles/s4158…, we started with a simple hypothesis - inspired by work on IL-4/IL-13 from Brian S. Kim - that an innate immune cell might control sensory neuronal detection of allergens via a secreted factor. (1/11)

OMG! 4 years of my life will be presented at #ERSCongress2024. For those not in the room, I will live tweet the results of the ABRA trial (Acute BenRAlizumab for exacerbations). Mona Bafadhel is setting off 🧵

🚨Organoid Postdoc Hiring🚨 Passionate about translational science using metabolomics & organoid models in childhood neurodevelopment? Join our team University of Surrey with Olivier Cexus, COPSAC Apply 👉 shorturl.at/3FWPy #Postdoc #Metabolomics #Organoid #Neurodevelopment

PhD position available kcl-mrcdtp.com/project/from-p…