SigniosBio (@signiosbio) 's Twitter Profile
SigniosBio

@signiosbio

AI-powered multiomics & bioinformatics. An affiliate of MedGenome. Global RWE to support discovery in oncology, rare disease & more. signiosbio.com

ID: 1905300656090714112

calendar_today27-03-2025 16:47:38

6 Tweet

8 Followers

1 Following

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What drives early-onset Parkinson’s (diagnosed ≤50) in India? Research involving Signios Bio, MedGenome & PRAI found PRKN variants are key contributors, especially in younger patients. hubs.ly/Q03hXDDP0 #ParkinsonsAwarenessMonth #YOPD #PDResearch #ScienceOfSignals

What drives early-onset Parkinson’s (diagnosed ≤50) in India? Research involving Signios Bio, MedGenome & PRAI found PRKN variants are key contributors, especially in younger patients. 
hubs.ly/Q03hXDDP0 
#ParkinsonsAwarenessMonth #YOPD #PDResearch #ScienceOfSignals
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Meet #SigniosBio (formerly MedGenome) at #AACR2025 — Booth 2364, April 25–30 in Chicago. Let’s talk multiomics in #oncology: solid tumors, heme, IO & more. Same expert team, new focus. #ScienceOfSignals Schedule a meeting: hubs.ly/Q03jn_V20 #Genomics #CancerResearch

Meet #SigniosBio (formerly MedGenome) at #AACR2025 — Booth 2364, April 25–30 in Chicago. Let’s talk multiomics in #oncology: solid tumors, heme, IO & more. Same expert team, new focus. #ScienceOfSignals Schedule a meeting: hubs.ly/Q03jn_V20 #Genomics #CancerResearch
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New Lung Cancer Case Study with Mukesh Nyati at #AACR2025! See how #SigniosBio's spatial transcriptomics mapped the TME in KRAS models. Discuss the findings with Dr. Nyati at Booth #2364 on Tuesday (29th) at 2pm! #SpatialTranscriptomics #CancerResearch #ScienceOfSignals

New Lung Cancer Case Study with <a href="/MukeshKNyati/">Mukesh Nyati</a> at  #AACR2025! See how #SigniosBio's spatial transcriptomics mapped the TME in KRAS models. Discuss the findings with Dr. Nyati at Booth #2364 on Tuesday (29th) at 2pm! #SpatialTranscriptomics #CancerResearch #ScienceOfSignals
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Meet #SigniosBio (formerly MedGenome) at #AACR25 — Booth 2364, April 25–30 in Chicago. Let’s talk multiomics in #oncology: solid tumors, heme, IO & more. Same expert team, new focus. #ScienceOfSignals Schedule a meeting: hubs.ly/Q03jn_V20 #Genomics #CancerResearch

Meet #SigniosBio (formerly MedGenome) at #AACR25  — Booth 2364, April 25–30 in Chicago. Let’s talk multiomics in #oncology: solid tumors, heme, IO &amp; more. Same expert team, new focus. #ScienceOfSignals Schedule a meeting: hubs.ly/Q03jn_V20 #Genomics #CancerResearch
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Happy #DNADay! "Genes are the foundation of humanity. We stand at the threshold of a new era—one that gives us the power to prevent or cure all genetically linked diseases." – Dr. Felix Olale, CEO, #SigniosBio Celebrating the power of #genomics to shape health. #Genetics #DNA

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Day 1 of #AACR25! Visit Signios Bio at Booth #2364. Let's talk multiomics for #oncology discovery - Solid Tumor, Heme, IO. Meet our scientific & bioinformatics experts onsite! #SigniosBio #CancerResearch #ScienceOfSignals Schedule time: hubs.ly/Q03j_hcj0

Day 1 of #AACR25! Visit Signios Bio at Booth #2364. Let's talk multiomics for #oncology discovery - Solid Tumor, Heme, IO. Meet our scientific &amp; bioinformatics experts onsite! #SigniosBio #CancerResearch #ScienceOfSignals
Schedule time: hubs.ly/Q03j_hcj0
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Happening Today! Join Mukesh Nyati at #AACR25 to hear how #SigniosBio's spatial transcriptomics mapped the TME in KRAS models. Catch Dr. Nyati at Booth #2364 at 2pm today to discuss the findings! #SpatialTransciptomics #CancerResearch #ScienceOfSignals

Happening Today! Join <a href="/MukeshKNyati/">Mukesh Nyati</a> at #AACR25 to hear how #SigniosBio's spatial transcriptomics mapped the TME in KRAS models. Catch Dr. Nyati at Booth #2364 at 2pm today to discuss the findings! 
#SpatialTransciptomics #CancerResearch #ScienceOfSignals
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See the bigger picture in cancer with #SigniosBio's PacBio #HiFi long reads. Detect SNVs, Indels, SVs, full-length RNA isoforms & DNA methylation (#5mC) in one workflow. Explore what's possible: hubs.ly/Q03klNb_0 #LongReads #CancerGenomics #Epigenetics #ScienceOfSignals

See the bigger picture in cancer with #SigniosBio's PacBio #HiFi long reads. Detect SNVs, Indels, SVs, full-length RNA isoforms &amp; DNA methylation (#5mC) in one workflow. Explore what's possible: hubs.ly/Q03klNb_0 #LongReads #CancerGenomics #Epigenetics #ScienceOfSignals
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Dissecting LUSC heterogeneity with scRNA-seq: See how researchers identified KLF4-driven hillock-like states in our new solid tumor profiling note. …743515.fs1.hubspotusercontent-na1.net/hubfs/46743515…. #CancerResearch #Genomics #SingleCell #SigniosBio #ScienceOfSignals

Dissecting LUSC heterogeneity with scRNA-seq: See how researchers identified KLF4-driven hillock-like states in our new solid tumor profiling note. …743515.fs1.hubspotusercontent-na1.net/hubfs/46743515…. #CancerResearch #Genomics #SingleCell #SigniosBio #ScienceOfSignals
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Researching #HematologicMalignancies? Check out our new application note to see solutions and how they helped researchers uncover microenvironment changes after GSI treatment in multiple myeloma hubs.ly/Q03l4T9p0 #SigniosBio #Hematology #Multiomics #ScienceOfSignals

Researching #HematologicMalignancies? Check out our new application note to see solutions and how they helped researchers uncover microenvironment changes after GSI treatment in multiple myeloma hubs.ly/Q03l4T9p0 #SigniosBio  #Hematology #Multiomics #ScienceOfSignals
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Short-read RNA-seq missing key cancer transcript details? #SigniosBio's long-read RNAseq provides full-length clarity on isoforms, fusions & splice variants. Get in touch to learn more. hubs.ly/Q03l4XHq0 #IsoSeq #HiFiSequencing #RNA #CancerResearch #ScienceOfSignals

Short-read RNA-seq missing key cancer transcript details? #SigniosBio's long-read RNAseq provides full-length clarity on isoforms, fusions &amp; splice variants. Get in touch to learn more. hubs.ly/Q03l4XHq0  #IsoSeq #HiFiSequencing #RNA #CancerResearch #ScienceOfSignals
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More data, less DNA. With #SPRQ chemistry, Signios Biosciences is unlocking #HiFisequencing for tough samples—boosting output and expanding access to more sample types. 🔗 See how they’re using SPRQ to scale impact and access: bit.ly/4jgpTbn #PacBio #PacBioSPRQ

More data, less DNA. With #SPRQ chemistry, Signios Biosciences is unlocking #HiFisequencing for tough samples—boosting output and expanding access to more sample types.
 
🔗 See how they’re using SPRQ to scale impact and access: bit.ly/4jgpTbn
 
#PacBio #PacBioSPRQ
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See beyond the genome with HiFi sequencing to directly map DNA methylation (5mC, no bisulfite!) & resolve complex SVs missed by short reads. Explore cancer epigenetics & genomics with #SigniosBio hubs.ly/Q03mDrqM0 #Hi

See beyond the genome with HiFi sequencing to directly map DNA methylation (5mC, no bisulfite!) &amp; resolve complex SVs missed by short reads. Explore cancer epigenetics &amp; genomics with #SigniosBio hubs.ly/Q03mDrqM0  #Hi
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Advancing #ImmunoOncology research? Check out our latest application note on how single-cell profiling revealed immunologic signatures of response and resistance to ICIs in metastatic cancer. hubs.ly/Q03mF0c00 #SigniosBio #ImmunoOncology #SingleCell #ScienceOfSignals

Advancing #ImmunoOncology research? Check out our latest application note on how single-cell profiling revealed immunologic signatures of response and resistance to ICIs in metastatic cancer. hubs.ly/Q03mF0c00 #SigniosBio #ImmunoOncology #SingleCell #ScienceOfSignals
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New grant alert! Illumina & Signios Bio are offering no-cost proteomic analysis (up to 170 samples, 9.5K proteins via NovaSeq) + expert support + a chance to present your work. Apply by June 27! Press release: hubs.ly/Q03nc1SW0 Apply: hubs.ly/Q03nc2wv0

New grant alert! Illumina &amp; Signios Bio are offering no-cost proteomic analysis (up to 170 samples, 9.5K proteins via NovaSeq) + expert support + a chance to present your work. Apply by June 27!
Press release: hubs.ly/Q03nc1SW0
Apply: hubs.ly/Q03nc2wv0
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It’s Alzheimer’s & Brain Awareness Month. Signios Bio supports brain research with Neuroregulation Signal (to identify vulnerable neurons) and Neuroimmune Signal (to map immune activity). Learn more: hubs.ly/Q03rZy6y0 #BrainAwarenessMonth #Neuroscience #ScienceOfSignals

It’s Alzheimer’s &amp; Brain Awareness Month. Signios Bio supports brain research with Neuroregulation Signal (to identify vulnerable neurons) and Neuroimmune Signal (to map immune activity). Learn more: hubs.ly/Q03rZy6y0
#BrainAwarenessMonth #Neuroscience #ScienceOfSignals
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For #BrainAwarenessMonth: Stanford study (w/ scRNA-seq + bioinformatics by Signios Bio) reveals 6 microglia-like cell subtypes in a model of progranulin deficiency (#FTD). New insights into CNS cell replacement. Preprint: hubs.ly/Q03rZDK-0 #scRNAseq #ScienceOfSignals

For #BrainAwarenessMonth: Stanford study (w/ scRNA-seq + bioinformatics by Signios Bio) reveals 6 microglia-like cell subtypes in a model of progranulin deficiency (#FTD). New insights into CNS cell replacement. Preprint: hubs.ly/Q03rZDK-0
#scRNAseq #ScienceOfSignals
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It’s still #BrainAwarenessMonth. Signios Bio supported scRNA-seq in a progranulin deficiency study, uncovering diverse microglia-like cells: hubs.ly/Q03rZzsC0 Explore our single-cell services: hubs.ly/Q03rZR7T0 #scRNAseq #Genomics

It’s still #BrainAwarenessMonth. Signios Bio supported scRNA-seq in a progranulin deficiency study, uncovering diverse microglia-like cells: hubs.ly/Q03rZzsC0
Explore our single-cell services: hubs.ly/Q03rZR7T0
#scRNAseq #Genomics
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#BrainAwarenessMonth: Prof. Theus (Virginia Tech) on #TBI research with Signios Bio: “…we validated signaling at the protein level and tested it therapeutically in our model.” Multiomics made it possible. Read the TBI story: hubs.ly/Q03rZXKD0 #Multiomics #ScienceOfSignals

#BrainAwarenessMonth: Prof. Theus (Virginia Tech) on #TBI research with Signios Bio: “…we validated signaling at the protein level and tested it therapeutically in our model.” Multiomics made it possible. Read the TBI story: hubs.ly/Q03rZXKD0 #Multiomics #ScienceOfSignals
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As #AlzheimersBrainAwarenessMonth ends, see how single-cell, spatial & long-read sequencing are used to study brain complexity in TBI, FTD, FA & Alzheimer’s. Read more: hubs.ly/Q03svdbM0 #NeuroscienceResearch #Genomics

As #AlzheimersBrainAwarenessMonth ends, see how single-cell, spatial &amp; long-read sequencing are used to study brain complexity in TBI, FTD, FA &amp; Alzheimer’s.
Read more: hubs.ly/Q03svdbM0
#NeuroscienceResearch #Genomics