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An interplay exists between our environment, biology and brain health. In Nature Communications we characterise molecular signatures of brain health in Generation Scotland participants. (1/8)nature.com/articles/s4146…

My first ever paper published today in JAMA Psychiatry! This project on genome-by-trauma exposure interaction effects was the highlight of my PhD and I’m very happy to be sharing this! jamanetwork.com/journals/jamap…

Many thanks to all co-authors (Xueyi Shen, Mark James Adams, Miruna Carmen Barbu, @HannahJaJo, @MironLab, Judith Allardyce, James P Boardman, Stephen Lawrie, Andrew McIntosh, Golam Khandaker, Alex Kwong, Heather Whalley), BBI Health reviewers, participants from Children of the 90s & funding from Wellcome 6/6

Terrific visit from Michael Fletcher Nature Genetics today - hearing about his career & the work of Nature Genetics

Happy to share my 1st paper, in Biological Psychiatry! We investigated the links between 249 circulating metabolites & Major Depressive Disorder (MDD) in UK Biobank. A thread 🧵 of our main findings:👇

ENIGMA Consortium Thanks for having us over, it was our pleasure! Looking forward to all the exciting talks at upcoming #SOBP2023 Big shout out to Xueyi Shen for all her hard work developing the PRS pipeline we used for these new projects!

Very grateful to Wellcome for funding our project on the mechanism of action of #lithium in #bipolardisorder (testing a light hypersensitivity hypothesis). Working with Bipolar Scotland and colleagues in Northumbria, Newcastle and Germany. Details at heliosbd.com

Excited to be funded by Wellcome for 5-year study to increase our understanding of antidepressant response. Fantastic partnership with Andrew McIntosh Heather Whalley Sue Fletcher-Watson @ScientistShah Quan Nguyen, Naomi Wray Oliver Pain PGC Consortium NIHR Maudsley Biomedical Research Centre (BRC) #DreamTeam

Thank you to everyone who contributed data & analysis skill sto this first PGC Consortium DNA Methylome-wide association analysis (MWAS) of #depression medrxiv.org/content/10.110…

Wow.. headsets provided for many ‘silent’ presentations to take place in one massive open space. New experience! Not very earring-friendly though 🤣

Great line up of speakers today Edinburgh Neuroscience Annual Day Conference today - including Xueyi Shen

Wow… 😮

I am delighted to announce my first first-author paper has just been published in JAMA Psychiatry! 🧬📈‘Genetic Architectures of Adolescent Depression Trajectories in 2 Longitudinal Population Cohorts’. Link to paper: ja.ma/4bkGsPj and a 🧵of our key findings below…

*Ten* 3-year post-doc/assistant prof jobs advertised for our Pioneer Centre for SMARTbiomed - address key questions in common complex diseases through development of new stat/comp tools & software. A new Denmark-Oxford collaboration. Critical mass! smartbiomed.dk/join-the-centr…

Didn’t know there was a huge windows IT outage. Although I know it shouldn’t affect my personal laptop, still git pushed all my projects today. It made me feel better..

Fab catch up with amazing collabs from University of Bristol and MRC IEU. Loads of cool stuff on mental health, omics, inflammation, population health and EHR. Looking forward to the continued working Golam Khandaker Andrew McIntosh

Wow! Can’t wait to try

Professor Ed Bullmore leads the ImmunoMIND hub based in Cambridge. Find out how the hub brings together international scientists and people with lived experience and why we need to think differently about SMI. Watch the video: buff.ly/4e0n7mX #mentalhealthresearch

The SMR Portal paper is now online. nature.com/articles/s4159…

1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in Cell. cell.com/cell/fulltext/… A thread 🧵: