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ISGyP 166.1Young woman.  Heavy bleeding.  Large mass prolapsing, filling whole vagina.  At hysterectomy appears to be arising from cervix. Diagnosis: Embryonal rhabdomyosarcoma. Comment: Embryonal rhabdomyosarcoma is a malignancy with a 5-year event-free survival of about 75%.

ISGyP 166.2 18-year-old female with 23cm ovarian mass. Diagnosis: Yolk sac tumour. Yolk sac tumors (also known as endodermal sinus tumors) are malignant primitive germ cell tumors; they are histologically similar to the mesenchyma of the primitive yolk sac.

ISGyP 166.3 33-year-old female with massive 15cm tumour arising in cervix displacing uterus.  Central exenteration including total vaginectomy. Diagnosis: NTRK-rearranged sarcoma.

ISGyP 166.4 39 years.  Hysterectomy for placenta accreta.  Submucosal fibroid noted. Diagnosis: Inflammatory myofibroblastic tumour.  ALK IHC and FISH positive. Inflammatory myofibroblastic tumor (IMT) is related to abnormalities in the ALK gene.

ISGyP 166.5 45 years, Cervix  Diagnosis: Gastric-type endocervical adenocarcinoma with micropapillary component. Minimal-deviation adenocarcinoma of the endocervix, also previously referred to as adenoma malignum, is now encompassed in the umbrella-gastric type adenocarcinomas.

ISGyP 166.6 23 years.  Right ovarian cyst.   Diagnosis: Poorly differentiated Sertoli-Leydig cell tumour with heterologous mucinous differentiation. Sertoli-Leydig cell tumors (SLCTs) are rare ovarian sex-cord stromal tumors. They account for less than 0.5% of all ovarian tumours

ISGyP 166.7 52 years female. Degenerating Fibroid: Diagnosis: Low grade stromal sarcoma with sex cord elements. JAZF1 FISH positive.

The Internet is not supporting my work PC, please guide

IT had a look they say it’s Telstra NBN issue so I need to sort from My end ie Telstra needs to fix it, I’m Not the first person others also had same issue and Telstra sorted it out for them!

I’m no more Able to access my work remotely, NBN is not allowing

ISGyP 167.1 18-year-old female with Swyer syndrome.  Left ovary. Diagnosis: Gonadoblastoma with Dysgerminoma. Swyer syndrome, also known as XY complete gonadal dysgenesis, is a rare genetic condition where individuals with a 46, XY karyotype streak gonads.

ISGyP 167.2; 35-year-old female who presented with 3/12 of amenorrhoea, nausea and headaches. Solid 10cm ovarian mass. Diagnosis: Small cell carcinoma of ovary, hypercalcaemic type.

ISGyP 167.3; 56 years, Cervix. Diagnosis: NTRK3-rearranged sarcoma. NTRK-rearranged sarcoma of the cervix is rare characterized by specific genetic rearrangements (NTRK1 or NTRK3 fusions) that make them responsive to targeted therapy with tropomyosin receptor kinase inhibitors.

ISGyp 167.4; 46 years, 3cm submucosal fibroid. Diagnosis: UTROSCT with retiform pattern and spindle cells. Calretinin, inhibin, SFT positive; TTF1, GATA3 negative. Uterine tumors infrequently exhibit ovarian sex cord-like features.

ISGyP 167.5; 53 years. Enlarging fibroid in menopause ?malignant. Diagnosis: Uterine sarcoma with GREB1-NCOA2 fusion. GREB1-NCOA fusion in uterine sarcoma, helps diagnose and potentially classify a rare subtype called Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT).

ISGyP 167.6; 25 years. Intrauterine nodular lesion noted at C/section ?fibroid ?placental tissue. Diagnosis: Adenosarcoma with sarcomatous overgrowth, aggressive type of uterine adenosarcoma where the sarcomatous (non-glandular) component makes up more than 25% of the tumor.