High-throughput, label-free detection of DNA origami in single-cell suspensions using origamiFISH-Flow ift.tt/v0tohqL #biorxiv_bioE

High-throughput, label-free detection of DNA origami in single-cell suspensions using origamiFISH-Flow (relevance: 65%) biorxiv.org/cgi/content/sh… #biophotonics #biomedicaloptics

Pre-print alert!!🚨Congratulations shana alexander! OrigamiFISH-Flow is an exciting method that provides us an opportunity to profile DNA nanostructure interactions with large cell populations. Leo Chou doi.org/10.1101/2023.1…

Huge congrats to my lab-mate shana alexander for getting her manuscript on origamiFISH-flow out! OrigamiFISH-Flow provides a new method to profile DNA nanostructure interactions with large cell populations. #DNA #nanotech

We now have a flow cytometry version of the origamiFISH method recently reported in Nat Nano. As before, it offers greater sensitivity compared to dye labels, now with high throughout and works with nonadherent cells. Give it a try! biorxiv.org/content/10.110…

Congrats to my awesome lab mate shana alexander for getting her paper published. Check it out here: …iley-com.myaccess.library.utoronto.ca/share/BDFA9MSH… She developed origamiFISH-Flow, a high-speed, label-free method to quantify DNA nano-structures in single-cell suspensions. #nanotech #PhD

Happy to announce our work has been published in Small! origamiFISH-Flow is high-throughput and has greater sensitivity over traditional dye-labeling for detection of DNA origami nanoparticles in cells and tissues. Check it out: doi.org/10.1002/smll.2…😀

Congrats to my PhD student shana alexander on publishing her first paper! Shana combined sensitive HCR FISH with flow cytometry to analyze distribution of synthetic DNA nanostructures in single cell suspensions. Label-free and way more sensitive than dye labeling!

shana alexander did an incredible job leading this project. This method combines HCR FISH with flow cytometry to offer a highly sensitive assay for detecting DNA nanostructures in cells, at bulk scale. doi.org/10.1002/smll.2… Congratulations, it was awesome working with you!

Massive!! Thank you so much Steve Will Do It

Researchers at the University of Toronto have made an advancement in DNA-based neural networks, paving the way for more portable and scalable molecular computers: discover.bme.utoronto.ca/researchers-de…

Honoured to have been able to present my research at the Bay Area Chemical Biology Symposium at Stanford these past few days. It was so inspiring connecting with students and faculty from the West Coast! Thank you Sarafan ChEM-H for a great event!

📍 Niagara Falls Half Marathon

Prof. Leo Chou has been awarded $130K in funding from the Cancer Research Society to propel forward an ambitious project aiming to boost the effectiveness of cancer vaccines: lnkd.in/guVc6AWy

Excited to share our most recent work in ACS Nano led by Travis Douglas where we manipulate antigen spacing on DNA origami nanoparticles to control immune complex formation! Congrats Travis! pubs.acs.org/doi/10.1021/ac…

Very excited to share our work, "Patterned Antigens on DNA Origami Controls the Structure and Cellular Uptake of Immune Complexes" published today in ACS Nano. 🧵 pubs.acs.org/doi/10.1021/ac…

ACS Nano Leo Chou Also big thanks to shana alexander for her dedication and help with the project. It’s awesome working with you!! Hope to collaborate again soon!!

Researchers from the Institute of Biomedical Engineering (BME) at the University of Toronto have developed a new method to precisely control the structure and function of immune complexes (ICs) using DNA origami: discover.bme.utoronto.ca/engineering-sy…

Just saw some pretty crazy numbers about the DNA nanotech market - projected to hit $25.57B by 2033. It's going to be cool to see new emerging DNA nanotech companies. finance.yahoo.com/news/dna-nanot… #DNANanotechnology #Diagnostics #Biotech