
Shaalan Beg MD MBA FASCO
@shaalanbeg
Reimagining cancer clinical trials.
Foodie, family guy, digital health.
FCOI: bit.ly/2MOSSWD
ID: 3031924044
https://www.linkedin.com/in/shaalanbeg 20-02-2015 03:07:06
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The NCTN, albeit imperfect, serves a critical role in advancing cancer care by: 1)Conducting pragmatic trials pharma/industry would never sponsor 2)Enrolling across a diverse network (>3K sites) representative of a “real world” population Great editorial Ted Hong Thomas George, MD, FACP, FASCO👏


Addressing Tumor Board Bad Habits and Risks: A Call for Rational Resource Management. ascopubs.org/doi/pdf/10.120… ASCO Journal of Clinical Oncology JCO Oncology Practice #CancerCare #MedEd #MedTwitter Jeffrey peppercorn MD


Claudin-18 isoform 2-specific CAR T-cell therapy vs treatment of physician’s choice for advanced GC/GJC The Lancet doi.org/10.1016/S0140-… 🔎 CT041-ST-01 phs 2 trial 👉first 🗺️randomised controlled trial of CAR T-cell therapy in solid tumours 👉Sign improved PFS ESMO - Eur. Oncology



Don’t forget: many landmark trials at #ASCO25 (e.g. ATOMIC, PDIGREE, CHALLENGE) were powered by National Cancer Institute / NCTN Such studies ask high-impact, public-benefit questions that industry often won’t/can't answer. Alliance for Clinical Trials in Oncology CCTG ECOG-ACRIN Cancer Research Group NRG Oncology SWOG Cancer Research Network


100% agree. There are questions that industry cannot answer, which requires alternative mechanisms which is where the National Cancer Institute and cooperative groups come in.


💯- the NCTN is complex but our trials are asking — and answering — many highly relevant questions for everyone that industry is not incentivized to answer. Alliance for Clinical Trials in Oncology ECOG-ACRIN Cancer Research Group SWOG Cancer Research Network NRG Oncology Children’s Oncology Group Nice editorial Ted Hong Thomas George, MD, FACP, FASCO academic.oup.com/jnci/advance-a…


Organizing Online Health Content: Developing Hashtag Collections for Healthier Internet-Based People and Communities [Jun 28, 2019] Matthew Katz, MD 🇺🇸🟦 et al. JCO Clinical Cancer Informatics ow.ly/AxNP30p1P6g #ayacsm #bcsm #btsm #gyncsm #lcsm #mmsm #pancsm #ASCO25
![Mike Thompson, MD, PhD, FASCO (@mtmdphd) on Twitter photo Organizing Online Health Content: Developing Hashtag Collections for Healthier Internet-Based People and Communities [Jun 28, 2019] <a href="/subatomicdoc/">Matthew Katz, MD 🇺🇸🟦</a> et al. <a href="/JCOCCI_ASCO/">JCO Clinical Cancer Informatics</a> ow.ly/AxNP30p1P6g #ayacsm #bcsm #btsm #gyncsm #lcsm #mmsm #pancsm #ASCO25 Organizing Online Health Content: Developing Hashtag Collections for Healthier Internet-Based People and Communities [Jun 28, 2019] <a href="/subatomicdoc/">Matthew Katz, MD 🇺🇸🟦</a> et al. <a href="/JCOCCI_ASCO/">JCO Clinical Cancer Informatics</a> ow.ly/AxNP30p1P6g #ayacsm #bcsm #btsm #gyncsm #lcsm #mmsm #pancsm #ASCO25](https://pbs.twimg.com/media/GtAKtoUWEAAxRf9.jpg)


Beyond Opioids: A Multidisciplinary Approach to #Cancer Pain Management. ascopubs.org/doi/pdf/10.120… ASCO Journal of Clinical Oncology JCO Oncology Practice #PallOnc #CancerCare #CancerResearch #SuppOnc Desiree Azizoddin, PsyD Dana-Farber






Nice summary of a balanced editorial on PANOVA-3 by Mike Pishvaian. Wow – 29% dropout rate is huge, & IMO diminishes the benefits of randomization. That 40 pts in TTF arm essentially requested withdrawal after 1 mo wearing the device & weren’t included in analyses = risk for bias.

