We're building Australia's first centre for the designing and manufacturing personalised cancer vaccines BASE mRNA Facility AIBN Research. On the PhaseIII podcast I discuss the transformative potential of mRNA for cancer and our efforts to bring this tech to patients podcasts.apple.com/au/podcast/vax…

Earlier this year I had the opportunity to present a TEDx talk on the transformative potential of personalised #mRNA vaccines for cancer. The recording is out now: youtube.com/watch?v=BnSOgJ… AIBN Research BASE mRNA Facility UQ News

Awesome work from Mike Mitchell at UPenn in nature identifies novel LNPs that can deliver #mRNA to the placenta. Using the placenta-targeting LNPs to deliver VEGF mRNA improves pre-eclampsia in animal models. nature.com/articles/s4158…

It was fantastic collaborate with Fernando Guimaraes on this programme to develop CAR-NK therapies for sarcoma with #mRNA tech. These mRNA-enhanced NK cells can eliminate cancer cells in vitro and in vivo. Out now in Clinical and Translational Medicine. Translational Research Institute AIBN Research BASE mRNA Facility

Exciting news! BASE mRNA Facility and Vaxxas have been awarded the $2M USD Biomedical Advanced Research and Development Authority (BARDA) Patch Forward Concept Stage Prize to develop thermostable needle-free mRNA vaccines! AIBN Research uq.edu.au/news/article/2…

Wow this is super cool! Single-cell resolution imaging of #mRNA-LNP biodistribution in cleared mouse bodies. nature.com/articles/s4158…

Opportunity for a bioinformatician to join the lab Peter Mac Research to help us identify new Immunotherapies. Please reach out for further details. Ad is for a post doc but research assistants considered. 💻 🧬. See link below.

Interested in undertaking a #PhD in the transformative field of #mRNA cancer vaccines? I have an earmarked PhD #scholarship available for an outstanding domestic student to join our team at UQ News and BASE mRNA Facility . If this sounds like you, get in touch. study.uq.edu.au/study-options/…

Exited to share our latest preprint! mRNA-LNPs are efficiently delivered to healthy livers, but what about liver tumours? Our postdoc Laura Leighton found liver tumours efficiently take up mRNA, enabling next generation mRNA-LNP cancer therapeutics. biorxiv.org/content/10.110…

A huge milestone for personalised #mRNA therapeutics for inherited disease! A baby with an ultra-rare mitochondrial disease was treated at UPenn with an mRNA-encoded gene-corrector. The mRNA was made to treat a single individual in just 7 months! nejm.org/doi/full/10.10…

To accelerate #mRNA vaccine and therapy research, I'm excited to share our end-to-end protocol for #mRNA design, synthesis and encapsulation in Nature Protocols. Protocol development by Laura Leighton, Natasha Chaudhary and Tim Mercer. BASE mRNA Facility nature.com/articles/s4159…