Including model building! 😍

Scientists for a day: DNA extraction, protein modelling and even confocal microscopy 👩‍🔬 What an interesting evening at #CNIOStopCancer! #NIGHTspain #EuropeanResearchersNight Madri+d Marie Skłodowska-Curie Actions

Thanks to #CNIOStopCancer colleagues for these two days of retreat full of ideas and inspiring talks. Shared time makes stronger teams!! 😃

CryoEM structure of the membrane attack complex (MAC), one of the immune system’s first responders. In combo with complement proteins, it forms pores on pathogens' membranes which leads to their lysis. Solved in 2018 and published on Nature Communications 3dproteinimaging.com/protein-imager…

Ku complexes sense the presence of viral DNA🧬 in the cytosol, but viruses fight back. You can learn how Vaccinia does so in our latest paper, another great collaboration with Laurence Pearl 🔥💚🚣‍♀️🛶♊️ nature.com/articles/s4146…

Mechanism discovered that helps viruses like monkeypox to block and evade our cellular defence system Nature Communications Oscar Llorca cnio.es/en/news/basic-…

NIHCOLE is a lncRNA that helps NHEJ to repair DNA breaks in hepatocellular carcinoma. We just described the mechanism in our last publication together with the labs of Puri Fortes and F. Moreno-Herrero. Check it out now in Cell Reports sciencedirect.com/science/articl…

Just out Cell Reports! Together with Llorca lab and Puri Fortes we show that Ku70-Ku80 and APLF establish a minimal complex sufficient to support DNA synapsis Centro Nacional de Biotecnología (CSIC) CNIO Stop Cancer APLF and long non-coding RNA NIHCOLE promote stable DNA synapsis in non-homologous end joining

Final version of our collaborative work with Bubeck Lab is out: Discovery of autophagy receptors/regulators via Alphafold2-multimer. Great work by Tarhan Ibrahim yasin tümtaş Fede Mirkin Virendrasinh Khandare

We are hiring! Two postdoctoral positions on Structural Biology at Centro Nacional de Biotecnología (CSIC) saco.csic.es/index.php/s/gF… @markvanraaij Instruct-ERIC SEBBM Soc Biofísica España Madri+d LifeHUB.CSIC #Cienciajobs

🗓️June 12th: Second round of Chaperones, Molecular Mechanisms and Structure at #CFM_MolChaperones. 👉This session will present recent advances and breakthroughs on R2TP and prefoldin complexes and their potential role in protein quality control. ➡Info: cnio.es/eventos/molecu…

📢 ¡Llega un nuevo CNIO - #CaixaResearch Frontiers Meeting #CFM_MolChaperones! Las chaperonas son proteínas clave en el mantenimiento de la estructura y función del resto de proteínas del cuerpo. Explora qué papel juegan en el cáncer. 👇 🔗bit.ly/3wIdZUk

Our lab is running the Cancer Research UK Race for Life to raise funds and awareness for #breastcancer. 1 in 2 people will get cancer in their lifetime. Thanks to life-saving research I am here to tell my story. Sponsor us through this link. Imperial Sciences CRUK Events London fundraise.cancerresearchuk.org/team/doryens-t…

Glad to present our latest results published today in nature revealing the activation mechanism of the AAA+-dependent IS21 transposase. Congrats to all the authors! CIB Margarita Salas (CSIC), CSIC Full story here: rdcu.be/dLZgB nature.com/articles/s4158… and brief summary below 👇🧵

#simposios #46congresosebbm S3.3. Reconstituting biology: towards building life-like systems from the bottom up 📍Sala 9+10 📢 Building a cellular architecture from scratch 🗣️Thomas Surrey Centre for Genomic Regulation (CRG)

#simposios #46congresosebbm 📢 S3.3. Reconstituting biology: towards building life-like systems from the bottom up 📍Sala 9+10 👥Coordina: Germán Rivas CIB Margarita Salas (CSIC) 🗣️Participan Thomas Surrey Centre for Genomic Regulation (CRG) , Javier Montenegro Montenegro Lab y James Pelletier Centro Nacional de Biotecnología (CSIC)

Pedro Temprano @brujer hace entrega del Premio José Tormo con pirita incluida a Marina Serna de CNIO Stop Cancer #46congresoSEBBM

#CNIOStopCancer researcher from Llorca lab Marina Serna, awarded for her contribution to solving a crucial biological problem.🔬 cnio.es/en/news/cnio-r…

The γTuRC saga goes on! This time, we used cryoEM to describe how CDK5RAP2 helps nucleating microtubules by activating the γTuRC nucleator. Another tour de force led by Marina Serna and Fabian Zimmermann and a fun collab with Jens Luders @LudersLab.bsky.social IRB Barcelona. authors.elsevier.com/c/1jpyq_Yv6zvB…

Logrado el primer mapa del espliceosoma, un talón de Aquiles del cáncer elpais.com/ciencia/2024-1…