How do cancer cells grow and organize themselves within a tumor??? See thread. sciencedirect.com/science/articl…

Would you like to do a #PhD in #DunLab #CSRG and help to develop a new immunotherapy for children’s brain cancers #DMG #DIPG #HGG #LGG newcastle.edu.au/study/research… Please like and share Huge thanks to the Little Legs Foundation for the support 💪

Incredible 2 day working group meeting designing the next arms of #PNOC022 #DMGACT with the most inspirational clinicians & fundamental scientists. Worth every km of the 34,000 to get here & back! So much to share w #DunLab #CSRG & much important work to do #DMG #DIPG RUNDIPG

The blood-brain barrier prevents many cancer therapies from reaching brain tumors. This year, the UCSF Brain Tumor Center will be opening multiple clinical trials that use focused ultrasound to safely and temporarily disrupt this barrier: braintumorcenter.ucsf.edu/news/focused-u… UCSF Helen Diller Family Comprehensive Cancer Ctr

Access to new drugs in paediatric oncology: can we learn from the ongoing ONC201 saga? ⁦The Lancet Oncology⁩ #DunLab, #CSRG ⁦Uni Newcastle Research⁩ ⁦Hunter Medical Research Institute (HMRI)⁩ ⁦RUNDIPG⁩ thelancet.com/journals/lanon…

We created a video with Dr. Sabine Mueller to share her best practices for newly diagnosed pediatric brain cancer patient families. youtu.be/YyaG4XaIkZk

My group is hiring local (Memphis) and contracting worldwide. We focus on pangenomics, chromosome biology, sequence analysis, machine learning (language/transformer and state space models), and data visualization (static, interactive, and art/science/outreach)

Happy to share our latest paper on self-supervised representation learning for live-cell microscopy with time arrow prediction (TAP). Great work by Ben Gallusser and Max Stieber ! arxiv.org/abs/2305.05511

Today, May 17, is DIPG/DMG Awareness Day. Throughout May, we have been creating and sharing images of the children who are the faces of DIPG/DMG, celebrating their lives and seeking to raise awareness of this awful disease. #MemoriesinMay #MovingTowardsACure

Wonderful to see our work on (deep) learning how to classify tumor types with WGS/WES data published in Genome Medicine! Great effort by Prima Sanjaya and coauthors to validate the method in >10,000 whole cancer genomes. FIMM HelsinkiUni Applied Tumor Genomics (ATG) iCAN - Digital Precision Cancer Medicine genomemedicine.biomedcentral.com/articles/10.11…

Now online in Cancer Discovery: Clinical Efficacy of ONC201 in H3K27M-mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways Koschmann Lab Vennetilab doi.org/10.1158/2159-8… Michigan Medicine U-M Rogel Cancer Center C.S. Mott Children's #DMG #DIPG

Excited to finally share our work investigating the efficacy of ONC201 in patients with H3K27M-mutant diffuse midline glioma (#DMG) published today Cancer Discovery! A tweetorial explainer🧵below by co-author Sunny Ji:

Clinical efficacy of ONC201 in H3K27M-DMG, by Vennetilab, Abed Rahman Kawakibi, Sunjong Ji, Sebastian Waszak, Stefan Sweha, Mateus Mota, Matthew Pun, Sharon Gardner, Yazmin Odia, Koschmann Lab et al. bit.ly/3qKO7Vh Michigan Medicine U-M Rogel Cancer Center C.S. Mott Children's #DMG #DIPG

#PNOC_kids is excited to present at #SNO2023 on the combination of ONC201+paxalisib in children & young adults with DMGs after completing RT. Preliminary results show that immediate OS significantly exceeds control data. Chimerix, Inc. Kazia Therapeutics ChadTough Defeat DIPG Foundation PNOC Foundation SNO

November issue— Clinical efficacy of ONC201 in H3K27M-#DMG, by Vennetilab, Abed Rahman Kawakibi, MD, Sunjong Ji, Sebastian Waszak, Stefan Sweha, Mateus Mota, Matthew Pun, Sharon Gardner, Yazmin Odia, Koschmann Lab et al. bit.ly/3QZMhKv Michigan Medicine U-M Rogel Cancer Center C.S. Mott Children's #DIPG

Commencing #BrainTumorAwarenessMonth by gathering Pediatric Neuro-Oncology experts worldwide, with gratitude to Dana-Farber for hosting us! Appreciating all who joined, whether virtually or in person. Anticipating continued progress following a fruitful meeting! #BTAM #PNOC