Thanks to our NCI PhysicalSciences colleague Russell Rockne and team for an absolutely wonderful and thought provoking collaborative few days City of Hope! @dbasanta and I are still thinking of the curry pizza 🍕 🤤
@dbasanta at #AACRevol23 gets us thinking about the difference between “data-driven” and “data-heavy”. Then talks about a hybrid agent-based model developed in his lab: Tackling the vicious cycle of bone remodeling in skeletal malignancies... #MoffittNews IMO
@dbasanta just touched on this recent Cancer Research paper in his interesting talk on taking a quantitative look at selection in somatic evolution and the role of the #TumorMicroenvironment during treatment at #AACRevol23 !
Excited to share the pre-print of the review @robjohnnoble.bsky.social, @dbasanta, Maciek Bąk and I have been working on!
In it, we outline a non-technical, step-by-step guide to designing a spatial agent based model of tumour evolution.
arxiv.org/abs/2311.03569
Todays IMO research in progress is from @dbasanta lab member tatiana.miti 🇺🇦 presenting on two different projects related to stromal sheltering in collaboration with Andriy Marusyk Moffitt Cancer Center
At #CSBCPSON23 , @dbasanta & Conor Lynch MoffittResearch are sharing the role of the bone microenvironment in #MultipleMyeloma relapse and the emergence of resistance to proteosome inhibitors.
Andriy discusses an unpublished collaboration with #AndersonLab & @dbasanta lab that looks at the protective interactions between sensitive and resistant cells. The agent based model was developed by 2 talented High school students: Rishi Shah & Sagnik Yarlagadda #AACRevol23
Using experimental approaches & #MathematicalModeling , 🌻Daria Miroshnychenko, tatiana.miti 🇺🇦, @dbasanta, Andriy Marusyk, et al. revealed a mechanism by which #TumorMicroenvironment -mediated #BreastCancer cell proliferation indirectly drives chemoresistance Cancer Research bit.ly/49OmBb7.
Matthew’s rotation will help connect our lab with the work of his advisor @dbasanta as well as Russell Rockne and Andriy Marusyk. Welcome to Moffitt Machine Learning Matthew!
#CSBCPSON23 : @dbasanta and Conor Lynch Moffitt Research are presenting how the #MultipleMyeloma bone #microenvironment ecosystem protects drug sensitive tumor cells, enabling the development of drug resistance.
It was fun writing and introspecting for #mathonco community, Thank you @dbasanta Jeffrey West and others of the Mathoncoblog for the opportunity.
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