Sophie de Carné
@sdecarne
Find me there → bsky.app/profile/sdecar…
Group Leader @gustaveroussy • Alumni @thecrick
#inflammation #cancer #RAS #prevention
ID: 491981974
https://bsky.app/profile/sdecarne.bsky.social 14-02-2012 07:01:46
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Visit of HERI Minister Sylvie Retailleau in London, at the occasion of the 1st 🇫🇷🇬🇧 dialog on Science & Technology Feb 28&29 3/5: Impressive visit to The Francis Crick Institute organised by UCL . Wonderful welcome by Sir Paul Nurse, visiting the amazing building, meeting scientists
Delighted to share our review on the impact of oncogenic KRAS on the tumour immune microenvironment and the potential for combining KRAS inhibitory drugs with immunotherapies. Cancer Cell #OpenAccess The Francis Crick Institute Miriam Molina Arcas authors.elsevier.com/sd/article/S15…
What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24, out in Cancer Discovery today rb.gy/q484j9 Tweetorial👇
Our paper is out! Excited to be part of such an amazing team unravelling the complexities of lung tumour/TME coevolution in #TRACERx Big thanks to all those involved in the project and who supported our work. Presented by Charles Swanton at #AACR24 Check out our Tweetorial below.
Check out our latest paper science.org/doi/10.1126/sc…. Congratulations to Evangelos Giampazolias who led the work. Thanks to very many who helped. Great collaboration with Tine Jess and Romina Goldszmid labs. Tweetorial will follow soon.
Excited to share our review on “Analyzing the functional effects of DNA variants with gene editing” Cell Reports Methods sciencedirect.com/science/articl… With recent advancements in saturation genome editing, base editing and prime editing, this is a rapidly progressing and exciting field!
Beyond excited to share our work on the reciprocal interaction between metastatic cancer cells and AT2 cells now published Developmental Cell ! 🧵 [1/15] cell.com/developmental-…
✨ Elles sont médecins, chercheuses, scientifiques à Gustave Roussy ✨ Dr Elsa Bernard est cheffe de groupe de l'équipe oncologie clinique computationnelle à Gustave Roussy. Découvrir son portrait ⤵
How can we extend responses to KRASG12C drugs? Out now in Nature Communications, combining Revolution Medicines’ RAS(ON) G12C-selective inhibitor with a SHP2 inhibitor and immune checkpoint blockade to study their effects on KRAS-mutant lung tumours of varying immunogenicities.