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Excited and deeply honored to receive the inaugural Biophysical Society Early Independent Career Award!! So grateful for this recognition, my collaborators, mentors, and most importantly, the The Barnes Lab team who make it all happen!! This award is truly ours!!! 🙌🏾🫶🏾🍾

Happy to announce that I will be moving across town in November to start a research group focused on solving a major (I think) molecular puzzle with serious implications in human health. Feel free to reach out!

Mark your calendars for the BPS CryoEM Subgroup Symposium, on Subgroup Saturday at Biophysical Society Annual Meeting 2025! Also, we have a new award, the Almeida Award, for a mid/senior level woman who has made outstanding contributions to #cryoem. See you there!

We are thrilled to welcome the incomparable Yiorgo Skiniotis and his lab! Yiorgo will also lead the new Center of Excellence for Structural Cell Biology, to advance cryoET and other cutting-edge approaches St. Jude Research, paving the way for new, exciting biological insights!

Our paper CryoBench: Diverse & challenging datasets for the heterogeneity problem in cryo-EM has been accepted at #NeurIPS2024 as a #spotlight! 🎉 🔗 Project: cryobench.cs.princeton.edu 📄 Paper: arxiv.org/pdf/2408.05526 💻 Code: github.com/ml-struct-bio/… Congrats to all authors!

Our article on the superworm pandemic is out in the Oct 3 print edition of Cell. Do any of my colleagues here subscribe to the print edition, and would you be willing to give me your copy when you're done with it? I'd love to keep a physical version.

Dear cryo-EM women scientists, We want to honor you and your contributions at BPS 2025. This year, the Cryo-EM subgroup will honor a mid/senior-career woman scientist as the inaugural June Almeida awardee. June Almeida is the virologist who first discovered the coronavirus in

Im so proud and excited to report that our very own talented graduate student Maymay Mu is one of the recipients of this years 2024 Audree Fowler Fellowship in Protein Science Very well deserved honor! UCLA Biological Chemistry UCLA MBI

CS vs RelionCor/CtfFind4 on the same 100 movies. Tried pretty much every setting in RelionCor/CtfFind4 but cannot get the CTF to be estimated well. The movies look good by eye and Thon rings are visible. Any ideas what to try if I was commited to use Relion/CTFfind?

This is damning. Another cryo-EM retraction and a paper based on zero data onlinelibrary.wiley.com/doi/10.1002/ad…

As of today, Lori Passmore and I will jointly lead the MRC Laboratory of Molecular Biology Structural Studies Division. 🥳 I am grateful to David Barford for his leadership in the past 9 years, 6 of which we did this together, and I very much look forward to this next stage with Lori! 😊

"Ever wondered how α-latrotoxin, the black widow spider's 🕷️ neurotoxin, turns into a cation-selective channel? Check out our latest manuscript! rdcu.be/dWez3 Nature Communications #Neuroscience #Toxin #cryoEM SFB 1348 Universität Münster

Maymay at her award seminar this morning. Many congratulations!! Very well deserved!

I would like snack on a bottle of #sigmaaldrichchocolate to fuel my science. Thanks Merck Life Science

New preprint out from the MonteRosa gang on computational approaches to mine the CRBN target space. Revealed new neosubstrates recognition modes including helical motifs and molecular surface mimicry. Lots to still learn about redirecting CRBN! biorxiv.org/content/10.110…

Yesterday a Nobel prize was given for alpha fold. Alpha fold could not exist without the Protein Data Bank (PDB), a public database funded by US taxpayers. Every structural biologist in the world that deposited their structure to the PDB indirectly helped train alpha fold.

Filomeno Sánchez Rodríguez et al.: Using deep-learning predictions reveals a large number of register errors in PDB depositions #DeepLearning #ProteinDataBank #StructureValidation @livuni @uniofyork... #IUCr journals.iucr.org/paper?S2052252…

It's happening! We're excited to be hosting ~300 attendees for the 9th SoCal CryoEM Symposium USC tomorrow. USC Dornsife College of Letters, Arts & Sciences USC Bridge Institute dornsife.usc.edu/bridge-institu…

👀❄️🔬Check it out from Jae Yang, Josh Mitchell, Craig Bingman, Deane Mosher, & me!! Tour de force of #cryoEM, #microED, #cryoET, & #cryoFIB to solve the in situ crystalline structure of the #Eosinophil major basic protein-1! biorxiv.org/cgi/content/sh… Congrats! ⁦UW–Madison Biochem⁩

hey #teamtomo if you are looking to add to your toolkit for molecular identification inside cells, our preprint is now out!