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Today’s episode of Dr. John Cush discusses TOC STOP service evaluation led by Vanessa Quick. - GCA relapse after cessation of TCZ. Many thanks to all who contributed 🙏 pubmed.ncbi.nlm.nih.gov/37952183/ podcasts.apple.com/gb/podcast/rhe…

🛑 Let’s stop saying #PMR and #GCA are “diseases of the elderly” 🛑 Excludes a large number who mightn’t see themselves as “elderly”. 🙍🏻🙍🏽‍♂️ academic.oup.com/rheumap/articl… here’s the published version of the study from the blog: When PMR strikes young, it hits hard. 📝

#Jaw claudication in #GiantCellArteritis Jaw stiffness affects ➡️Mouth opening ➡️Talking ➡️Teeth cleaning ➡️Accommodating cutlery Leads to ➡️Eating more slowly ➡️Soft or liquid diet ➡️Weight loss 👉🏽academic.oup.com/rheumap/articl… By Sarah Mackie @[email protected] et al Rheumatology & Rheumatology Advances in Practice

Wonderful story about how Sir Humphrey Davy would write poetry as an integral part of his own scientific creative process. theguardian.com/science/2023/d…

The STERLING-PMR trial has been approved for the NIHR Research Associate PI scheme! Applications welcome - further details here nihr.ac.uk/health-and-car…

Another successful AQUIRE (Audit, QUality improvement, Innovation, Research & Evaluation) event, thanks to Rabina Tindale for opening the event, to Sarah Mackie @[email protected], Teresa & Kathryn for reminding us about the importance of involving patients who can offer ideas for research!

Just published: the scope for the new update for our PMR clinical guideline. Hear about the plans from lead authors, what will be covered, and how the revision will support patients. bit.ly/4bDXqso Sarah Mackie @[email protected] Dr Max Yates Task Toyoda Janice Maddock Polymyalgia+GCA

Amazing atlas for polymyalgia rheumatica made by David Liew Claire Owen and colleagues Full text available Rheumatology & Rheumatology Advances in Practice BSR #polymyalgia #PETCT bit.ly/3w0XC4G

Important reading about devices (including algorithms) used for health measurement or prediction: Whitehead review on equity in medical devices. Much to ponder. liverpool.ac.uk/research/resea…

Glucocorticoids (GC), like dexamethasone and prednisolone, are widely used in medicine, but how do they actually work? This is really impressive work (Auger et al.), which figured it all out There are two mechanisms: a slow, broad response, which depends on transcriptional

An investigation of fibroblast activation protein (FAP) in giant cell arteritis found FAP was abundantly expressed by fibroblasts in GCA arteries FAP may be involved in the inflammatory and remodeling processes in GCA In AC&R loom.ly/PAKK4lY Vasculitis Groningen

Been thinking about this lovely episode of Casual Inference Podcast in which @lucystats and @epiellie talk to Aaditya Ramdas about sequential/safe anytime-valid inference. podcasts.apple.com/gb/podcast/cas… Here’s what I took away from the podcast episode, thinking mostly about #clinicaltrials (hope

Inspired by our last Annual Conference? Want to help shape the biggest rheumatology event of 2025? In the clip below 🩺 Dr Max Yates outlines the benefits of submitting a session and shares advice on impactful content! Submit a #BSR25 session by 3 June: bit.ly/4bGFX1N

Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation academic.oup.com/rheumatology/a…

PMR patients get too much steroid. Data across 27 million people in England, n=39,438 with PMR. The blue are getting more pred than guidelines. Like everything in rheum: we need to be giving less pred, not more. Lumping PMR in with GCA won’t help. #EULAR2024 POS0411 Dr. John Cush

Rheumatologists see a different part of the #GiantCellArteritis #GCA spectrum than ophthalmologists. What does this mean for diagnosis, treatment and care? Read this review in full #OpenAccess here: nature.com/articles/s4143… Sarah Mackie @[email protected] #Ophthalmology #FOAMed

🚨Largest GWAS of #PolymyalgiaRheumatica to date finds 3 new loci: -IL1R1 -NEK6 -CCDC88B 🚨MR shows associations between: -Smoking -Visceral adiposity -Multiple proteins relevant to IL-1 signalling and #PMR risk Rheumatology & Rheumatology Advances in Practice Sarah Mackie @[email protected] Shuai Yuan academic.oup.com/rheumatology/a…

Our recent review on the spectrum of giant cell arteritis: part of special issue of Eye Dr Susan Mollan #giantcellarteritis #GCA #PMR #FOAMed BSR NIHR Leeds BRC Borsha kate smith Vanessa Quick Khalique, M.I., Arjunan, M., Wood, S. et al. The spectrum of giant cell